推荐产品
表单
solid
颜色
off-white
溶解性
H2O: 18 mg/mL
DMSO: 6.3 mg/mL
SMILES字符串
Cl.N[C@@](CF)(Cc1c[nH]cn1)C(O)=O
生化/生理作用
Histidine decarboxylase inhibitor.
法规信息
新产品
K Sugimoto et al.
Journal of neurochemistry, 65(2), 791-797 (1995-08-01)
The mast cell-deficient [Ws/Ws (White spotting in the skin)] rat was investigated with regard to the origin of histamine in the brain. No mast cells were detected in the pia mater and the perivascular region of the thalamus of Ws/Ws
G D Prell et al.
Journal of neurochemistry, 66(5), 2153-2159 (1996-05-01)
In mammalian brain, histamine is known to be metabolized solely by histamine methyltransferase (HMT), forming tele-methylhistamine (t-MH), then tele-methylimidazoleacetic acid (t-MIAA). We previously showed that imidazoleacetic acid (IAA), a GABA agonist, and histamine's metabolite in the periphery, is present in
Long-term depletion of brain histamine induced by α-fluoromethylhistidine increases feeding-associated locomotor activity in mice with a modulation of brain amino acid levels.
Sakai, et al.
Behavioural Brain Research, 14, 83-88 (1995)
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