跳转至内容

Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

For important updates on recent policy changes, please click here for more details.

Merck
CN
所有图片(1)

主要文件

查看所有文档

安全信息

F1147

Sigma-Aldrich

Fumonisin B1 来源于串珠镰刀菌

≥98% (HPLC)

别名:

Macrofusine

登录查看公司和协议定价

选择尺寸

0.2 ML
¥8,960.87

¥8,960.87

国内现货，预计发货时间2025年4月23日详情

所有图片(1)

选择尺寸

变更视图
0.2 ML
¥8,960.87

About This Item

经验公式（希尔记法）:
C34H59NO15
CAS号:
116355-83-0
分子量:
721.83
MDL编号:
MFCD27977580
UNSPSC代码:
12352200
PubChem化学物质编号:
24894752
NACRES:
NA.32

¥8,960.87

国内现货，预计发货时间2025年4月23日详情

生物来源

Fusarium sp. (Fusarium moniliforme)

质量水平

300

方案

≥98% (HPLC)

表单

powder

溶解性

methanol: 9.80-10.20 mg/mL, clear, colorless to light yellow

储存温度

2-8°C

SMILES字符串

CCCC[C@@H](C)[C@@H](OC(=O)C[C@@H](CC(O)=O)C(O)=O)[C@H](C[C@@H](C)C[C@H](O)CCCC[C@@H](O)C[C@H](O)[C@H](C)N)OC(=O)C[C@@H](CC(O)=O)C(O)=O

InChI

1S/C34H59NO15/c1-5-6-9-20(3)32(50-31(44)17-23(34(47)48)15-29(41)42)27(49-30(43)16-22(33(45)46)14-28(39)40)13-19(2)12-24(36)10-7-8-11-25(37)18-26(38)21(4)35/h19-27,32,36-38H,5-18,35H2,1-4H3,(H,39,40)(H,41,42)(H,45,46)(H,47,48)/t19-,20+,21-,22+,23+,24+,25+,26-,27-,32+/m0/s1

InChI key

UVBUBMSSQKOIBE-DSLOAKGESA-N

正在寻找类似产品? 访问 产品对比指南

比较类似商品

查看完整比较结果

显示差异

1 of 4

此商品
SU860103SU860174SU860102
Magnetic Screw Cap for Headspace Vials, 18 mm thread PTFE/silicone septum (white PTFE/tranparent blue silicone), septum thickness 1.3 mm, pkg of 100 ea

SU860101

Magnetic Screw Cap for Headspace Vials, 18 mm thread

Magnetic Screw Cap for Headspace Vials, 18 mm thread PTFE/silicone septum (white PTFE/blue silicone), septum thickness 1.5 mm, pkg of 100 ea

SU860103

Magnetic Screw Cap for Headspace Vials, 18 mm thread

Universal Screw Cap, ND18 for Headspace Vials Ultra-clean, solid-top cap, septum thickness 1.3 mm

SU860174

Universal Screw Cap, ND18 for Headspace Vials

Magnetic Screw Cap for Headspace Vials, 18 mm thread PTFE-faced butyl septum (grey PTFE/red Butyl), septum thickness 1.6 mm, pkg of 100 ea

SU860102

Magnetic Screw Cap for Headspace Vials, 18 mm thread

material

PTFE/silicone septum (white PTFE/tranparent blue silicone), stainless steel screw cap (magnetic, open-top, 8 mm center hole)

material

PTFE/silicone septum (white PTFE/blue silicone), stainless steel screw cap (magnetic, open-top, 8 mm center hole)

material

red PTFE/white silicone septa, stainless steel screw cap (magnetic)

material

PTFE-faced butyl septum (grey PTFE/red Butyl), stainless steel screw cap (magnetic, open-top, 8 mm center hole)

fitting

thread for 18 mm

fitting

thread for 18 mm

fitting

thread for screw cap headspace vial (ND18)

fitting

thread for 18 mm

hardness

35 (Durometer: shore A)

hardness

60 (Durometer: shore A, durometer)

hardness

45 (Durometer: shore A)

hardness

55 (Durometer: shore A)

packaging

pkg of 100 ea

packaging

pkg of 100 ea

packaging

pkg of 1 × 100 ea (SU860174)

packaging

pkg of 100 ea

O.D. × H

18 mm × 11 mm

O.D. × H

18 mm × 11 mm

O.D. × H

-

O.D. × H

18 mm × 11 mm

一般描述

伏马菌素B1是一种霉菌毒素，存在于许多镰刀菌真菌，例如串珠镰刀菌、层出镰孢菌和拟轮生镰刀菌。 这种毒素也存在于被镰刀菌感染的原料和食品，例如玉米。

伏马菌素B1（FB1）与鞘氨醇结构相似。 因此，伏马菌素B1可以抑制神经酰胺合成酶（鞘氨醇N-乙酰基转移酶），其可导致神经酰胺生物合成和复杂鞘脂生物合成的中断。[1]

应用

来自霉菌镰刀菌的伏马菌素B1已被用于：
  • 对从成年猪盲肠内容物中的真菌毒素进行分析的标准品
  • 研究伏马菌素B1对朊病毒蛋白（PrP）异构体的代谢和羊瘙痒病朊病毒蛋白PrPSc合成的影响，以及
  • 研究伏马毒素B1对猪空肠外植体的毒性作用。[2][3][4]

生化/生理作用

伏马菌素B1可作为肝致癌物，并在大鼠中引起肝毒性。它在马中会引起白脑脑炎，而在猪中会引起肺水肿综合征。在中国和非洲南部地区，它与人类食道癌的高发有关。它可充当鞘氨醇N-酰基转移酶（神经酰胺合成酶）的抑制剂，[1]这与伏马菌素B1和鞘氨醇碱基（如鞘氨醇）之间的结构相似性有关。
真菌代谢物据信可引起马脑白质软化症。

象形图

Skull and crossbonesHealth hazard
GHS06,GHS08

警示用语：

Danger

危险分类

Acute Tox. 3 Oral - Carc. 2 - Repr. 2 - STOT RE 2

靶器官

Kidney,Liver

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

高风险级别生物产品--毒素类产品
  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000427375
    0000427375
    0000396984
    0000332746
    0000332747

    没有发现合适的版本？

    如果您需要特殊版本，可通过批号或批次号查找具体证书。

    搜索COA

    已有该产品？

    在文件库中查找您最近购买产品的文档。

    访问文档库

    Karina Basso et al.
    Toxins, 5(12), 2341-2352 (2013-11-30)
    Fusariotoxins such as fumonisin B1 (FB1) and deoxynivalenol (DON) cause deleterious effects on the intestine of pigs. The aim of this study was to evaluate the effect of these mycotoxins, alone and in combination, on jejunal explants from piglets, using
    Pranitha Dawlal et al.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 36(2), 296-307 (2019-01-25)
    Consumption of fumonisin-contaminated foods has a negative influence on the health of humans (carcinogen; oesophageal cancer in Eastern Cape in South Africa). Lactic acid bacteria (LAB) have emerged as a promising natural detoxification agent against mycotoxins. The aim of this
    Inhibition of Protein Serine/Threonine Phosphatases by Fumonisin B1, a Mycotoxin.
    Fukuda H
    Biochemical and Biophysical Research Communications, 220, 160-165 (1996)
    Judit Fodor et al.
    Food additives and contaminants, 24(4), 416-420 (2007-04-25)
    There is a lack of information on the effect of swine caecal microbiota on fumonisin metabolism. In this in vitro study, the biotransformation of fumonisin B(1) (FB(1)) by the gut microbiota of adult, healthy pigs was examined. Suspensions of caecal
    N Naslavsky et al.
    The Journal of biological chemistry, 274(30), 20763-20771 (1999-07-20)
    Sphingolipid-rich rafts play an essential role in the posttranslational (Borchelt, D. R., Scott, M., Taraboulos, A., Stahl, N., and Prusiner, S. B. (1990) J. Cell Biol. 110, 743-752)) formation of the scrapie prion protein PrP(Sc) from its normal conformer PrP(C)
    查看所有相关文献

    我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

    联系客户支持