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Merck
CN

F107

Sigma-Aldrich

氟桂嗪 二盐酸盐

别名:

1-[双(4-氟苯基)甲基]-4-(3-苯基-2-丙烯基)哌嗪 二盐酸盐

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About This Item

经验公式(希尔记法):
C26H26F2N2 · 2HCl
CAS号:
分子量:
477.42
Beilstein:
4284243
EC 号:
MDL编号:
UNSPSC代码:
12352203
PubChem化学物质编号:

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

forensics and toxicology
veterinary

SMILES字符串

Cl[H].Cl[H].Fc1ccc(cc1)C(N2CCN(CC2)C\C=C\c3ccccc3)c4ccc(F)cc4

InChI

1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;;

InChI key

RXKMOPXNWTYEHI-RDRKJGRWSA-N

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生化/生理作用

阻断 T 型 Ca2+/Na+ 通道。
阻断 T 型 Ca2+/Na+ 通道;抑制嗜铬细胞中由 K+ 诱导的儿茶酚胺释放。

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价格

象形图

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警示用语:

Warning

危险声明

预防措施声明

危险分类

Acute Tox. 4 Oral

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Behavioural brain research, 228(1), 144-150 (2011-12-20)
The motivational component of drug withdrawal may contribute to drug seeking and relapse through the negative reinforcement-related process; thus, it is important to understand the mechanisms that mediate affective withdrawal behaviors. The present study was undertaken to examine the calcium-dependent
Qing Ye et al.
Chinese medical journal, 124(17), 2649-2655 (2011-11-02)
Although flunarizine has been widely used for migraine prophylaxis with clear success, the mechanisms of its actions in migraine prophylaxis are not completely understood. The aim of this study was to investigate the effects of flunarizine on tetrodotoxin-resistant Na(+) channels
Carlijn El Hoekstra et al.
The Cochrane database of systematic reviews, (7)(7), CD007960-CD007960 (2011-07-08)
Tinnitus is the perception of sound or noise in the absence of an external or internal acoustic stimulation. It is a common and potentially distressing symptom for which no adequate therapy exists. To assess the effectiveness of anticonvulsants in patients
Ning Luo et al.
Pain medicine (Malden, Mass.), 13(1), 80-86 (2012-01-12)
The objective of this study was to observe the efficacy, safety, and side effects of a combination of flunarizine plus topiramate compared with either flunarizine and or toparamate alone for migraine prophylaxis. Out of 150 patients with migraine recruited into

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