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线性分子式:
C15H14ClN3O3 · 1/2 ZnCl2
化学文摘社编号:
分子量:
387.89
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
238-777-5
MDL number:
Colour Index Number:
37155
产品名称
固蓝RR盐, crystalline
InChI key
LLARVKAOQLUCQI-UHFFFAOYSA-L
InChI
1S/2C15H13N3O3.4ClH.Zn/c2*1-20-13-9-12(18-16)14(21-2)8-11(13)17-15(19)10-6-4-3-5-7-10;;;;;/h2*3-9H,1-2H3;4*1H;/q;;;;;;+2/p-2
SMILES string
[Cl-].[Cl-].Cl[Zn]Cl.COc1cc([N+]#N)c(OC)cc1NC(=O)c2ccccc2.COc3cc([N+]#N)c(OC)cc3NC(=O)c4ccccc4
form
crystalline
technique(s)
microbe id | staining: suitable
solubility
water: 1 mg/mL, clear to hazy, yellow-green
ε (extinction coefficient)
≥15000 at 326-332 nm
≥7000 at 390-396 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
Quality Level
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Application
固蓝RR盐已用于免疫组织化学中,以检测碱性磷酸酶的活性。 它已用于使用天狼猩红的结缔组织染色过程。
Biochem/physiol Actions
固蓝RR主要用于组织学染色。它可与碱性磷酸酶的反应产物结合,并使其作为不溶性化合物而沉淀。碱性磷酸酶活性的位点呈现黑色。固蓝RR也可用于检测酯酶活性。它可与萘酚(从萘酚乙酸酯中释放)偶联,形成不溶的偶氮染料,呈红色/蓝色。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Advances in Molecular Toxicology (1998)
Culling CFA
Handbook of Histopathological and Histochemical Techniques (2013)
Mesodermal expression of Fgfr2S252W is necessary and sufficient to induce craniosynostosis in a mouse model of Apert syndrome.
Holmes G and Basilico C
Developmental Biology, 368, 283-283 (2012)
Effects of T-lymphocyte depletion on muscle fibrosis in the mdx mouse.
Morrison J, et al.
The American Journal of Pathology, 166, 1701-1701 (2005)
Philip F Dobson et al.
Scientific reports, 10(1), 11643-11643 (2020-07-17)
The pathogenesis of declining bone mineral density, a universal feature of ageing, is not fully understood. Somatic mitochondrial DNA (mtDNA) mutations accumulate with age in human tissues and mounting evidence suggests that they may be integral to the ageing process.
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