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主要文件

EPS001

Sigma-Aldrich

HAT Activator, CTPB

A potent activator of HAT (histone acetyltransferase)

别名:

Benzamide, N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecyl, CTPB, CTPB (enzyme activator), CTPB (enzyme inhibitor), N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide

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选择尺寸

50 μG
¥4,485.99

¥4,485.99


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选择尺寸

变更视图
50 μG
¥4,485.99

About This Item

经验公式(希尔记法):
C31H43ClF3NO2
分子量:
554.13
UNSPSC代码:
12352200

¥4,485.99


请联系客服了解存货情况

方案

≥97% (H-NMR)

储存条件

desiccated
protect from light

颜色

white to off-white

溶解性

DMSO: soluble

储存温度

−20°C

InChI

1S/C31H43ClF3NO2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-18-24-19-17-20-28(38-4-2)29(24)30(37)36-25-21-22-27(32)26(23-25)31(33,34)35/h17,19-23H,3-16,18H2,1-2H3,(H,36,37)

InChI key

OYBMVMAXKOGYDC-UHFFFAOYSA-N

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此商品
GE17009002GE17009010G2580
particle size

163 μm (in methanol max.), 27 μm (In Methanol Min.), 18-111 μm (dry)

particle size

163 μm (in methanol max.), 18-111 μm (dry), 27 μm (In Methanol Min.)

particle size

163 μm (in methanol max.), 18-111 μm (dry), 27 μm (In Methanol Min.)

particle size

-

manufacturer/tradename

Cytiva 17-0090-01

manufacturer/tradename

Cytiva 17-0090-02

manufacturer/tradename

Cytiva 17-0090-10

manufacturer/tradename

-

packaging

pack of 100 g

packaging

pack of 500 g

packaging

pack of 25 g

packaging

-

feature

autoclavable 20 min at 121°C

feature

autoclavable 20 min at 121°C

feature

autoclavable 20 min at 121°C

feature

-

cleaning in place

2-13

cleaning in place

2-13

cleaning in place

2-13

cleaning in place

-

一般描述

(N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide) or CTPB, which is a non-polar compound, has been shown to enhance the neurite growth and survival of neuronal cell lines.[1][2]
A potent activator of p300 HAT (histone acetyltransferase), but not of PCAF (p300/CBP-associated factor) HAT activities.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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    访问文档库

    Small molecule modulators of histone acetyltransferase p300
    Karanam B et al.
    The Journal of Biological Chemistry (2003)
    A small molecule activator of p300/CBP histone acetyltransferase promotes survival and neurite growth in a cellular model of Parkinson?s disease
    Shane VH et al.
    Neurotoxicity Research, 30(3), 510-520 (2016)
    Shufeng Li et al.
    OncoTargets and therapy, 13, 12383-12395 (2020-12-11)
    Cervical squamous cell carcinoma (CSCC) is responsible for 80-85% of cervical cancer. Cyclin B1 (CCNB1) represents a hub gene during the development of cervical cancer. However, the oncogenic role of CCNB1 in CSCC remains unclear. Our study aims to explore

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