描述
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质量水平
产品线
MISSION®
形式
lyophilized powder
esiRNA cDNA靶序列
TCCCTTCATGAATGTAAGACTTCTAGTTCTGTATGAAGTGAGGCCATTTTGATTGTAAGCCATAGAAGTTCAGCAAGTAGCCAGGATGCCAGCCTAACTCTAGACTTGCTGTTGTTCTCAGATACTAACATTGAGTTGCAAACCTTAATTTCTGCGACGTGTTCTGCTGCACTTTTCCTTAAAGTACTCCTAGTATGTGGCCAGCAGACCTTGGAAGAGAACGCTCCTGCTTACAAACCCTGCTTTGGTTTTCATTTTAAGTCTGCGGAGTTTTGTTTTGTATTAAGGAATGTATAGACTGTACTACAGATAGAAAATAGTCTTTGTTTGTTCTACTTAAGAGAAACCGCTTAGGAAGCTATTGAAAGACACTTTGTTCTTTAAAGATCTTAAGATCAAGCCAATTTCATGAAACAATATTCCCAGAGAGTAATATATGTACTAGAGTAAAGAAGAAAATACTGACCTAATACAACGAGAACAATAATGTCTGCCTCTTAGAAGCTGGAG
基因组数据库 |小鼠登记号
NCBI登记号
运输
ambient
储存温度
−20°C
基因信息
mouse ... DCTN4(67665) , Dctn4(67665)
一般描述
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
法律信息
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Leticia M Ignacio-Souza et al.
Endocrinology, 155(8), 2831-2844 (2014-06-04)
In both human and experimental obesity, inflammatory damage to the hypothalamus plays an important role in the loss of the coordinated control of food intake and energy expenditure. Upon prolonged maintenance of increased body mass, the brain changes the defended
Kaori Kojima et al.
Neuroscience letters, 581, 37-41 (2014-08-26)
p62, which is also called sequestosome 1 (SQSTM1), plays a critical role in neuronal cell death. However, the role of p62 in axonal degeneration remains unclear. We evaluated whether the modulation of p62 expression may affect axonal loss in tumor
Young-Ok Son et al.
The Journal of biological chemistry, 289(41), 28660-28675 (2014-08-27)
The cadmium-transformed human lung bronchial epithelial BEAS-2B cells exhibit a property of apoptosis resistance as compared with normal non-transformed BEAS-2B cells. The level of basal reactive oxygen species (ROS) is extremely low in transformed cells in correlation with elevated expressions
Young-Ok Son et al.
The Journal of biological chemistry, 290(45), 27090-27100 (2015-09-20)
Arsenic (As(3+)) is a carcinogen with considerable environmental and occupational relevancy. The present study shows that As(3+)-transformed human lung bronchial epithelial BEAS-2B cells (AsT cells) exhibit the property of apoptosis resistance. The level of basal reactive oxygen species (ROS) is
Ashwani Khurana et al.
Oncotarget, 6(34), 36354-36369 (2015-10-27)
A promising new strategy for cancer therapy is to target the autophagic pathway. In the current study, we demonstrate that the antimalarial drug Quinacrine (QC) reduces cell viability and promotes chemotherapy-induced cell death in an autophagy-dependent manner more extensively in
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