描述
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质量水平
产品线
MISSION®
形式
lyophilized powder
esiRNA cDNA靶序列
GCTCAGGTTGCCAAAGAAAGTGTGCTCCAGTTCCACCCCCAAGCCAACATTGAGGCTCACCATGACAGCATCATGAACCCAGACTATAATGTGGAGTTTTTTCGACAGTTTATATTGGTCATGAATGCATTAGATAACAGAGCTGCACGAAACCACGTGAATAGGATGTGTCTGGCCGCTGATGTGCCTCTCATTGAGAGCGGGACTGCTGGGTATCTCGGACAGGTGACCACTATCAAGAAGGGTGTGACTGAGTGTTACGAATGTCACCCTAAGCCTACCCAGAGGACGTTCCCTGGCTGTACGATTCGGAACACGCCTTCAGAACCTATCCATTGCATCGTATGGGCCAAGTATTTGTTCAACCAGCTGTTTGGAGAGGAAGATGCTGATCAAGAAGTGTCTCCTGACAGAGCTGACCCTGAGGCTGCTTGGGAACCAACAGAGGCTGAAGC
基因组数据库 |小鼠登记号
NCBI登记号
运输
ambient
储存温度
−20°C
基因信息
mouse ... UBA2(50995) , Uba2(50995)
一般描述
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
法律信息
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Xingyue He et al.
PloS one, 10(4), e0123882-e0123882 (2015-04-11)
SUMOylation is a post-translational ubiquitin-like protein modification pathway that regulates important cellular processes including chromosome structure, kinetochore function, chromosome segregation, nuclear and sub-nuclear organization, transcription and DNA damage repair. There is increasing evidence that the SUMO pathway is dysregulated in
Xiaoke Liu et al.
Journal of hematology & oncology, 8, 67-67 (2015-06-13)
SUMO-activating enzyme subunit 2 (SAE2) is the sole E1-activating enzyme required for numerous important protein SUMOylation, abnormal of which is associated with carcinogenesis. SAE2 inactivation was recently reported to be a therapeutic strategy in cancers with Myc overexpression. However, the
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