描述
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质量水平
产品线
MISSION®
表单
lyophilized powder
esiRNA cDNA靶序列
GAGCAGAGAAGAAGCCTGGAGCGGGCCAGGACCGAGGACTATTTGAAACGGAAGATCCGTTCCCGGCCCGAGAGAGCAGAGCTGGTCAGGATGCACATTCTGGAAGAGACCTCGGCTGAGCCTTCGCTCCAGGCCAAGCAGCTGAAGCTGAAGAGAGCCAGGCTGGCTGATGACCTCAATGAAAAGATTGCACAGAGGCCTGGCCCCATGGAGCTGGTGGAGAAGAATATCCTGCCTGTGGAGTCCAGCCTGAAGGAGGCTATCATTGTGGGCCAGGTAAATTACCCAAAGGTAGCAGACAGTTCCTCCTTCGACGAGGACAGCAGCGATGCCCTGTCTCCTGAGCAGCCTGCCAGCCATGAGTCCCAGGGTTCAGTGCCATCACCCTTGGAGTCCCGAGTCAGTGATCCACTGCCCAGTGCCACCTCCATATCACC
基因组数据库 |小鼠登记号
NCBI登记号
运输
ambient
储存温度
−20°C
基因信息
mouse ... MKL1(223701) , Mkl1(223701)
一般描述
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
法律信息
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Xu Shiwen et al.
PloS one, 10(5), e0126015-e0126015 (2015-05-09)
In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of disabling symptoms. Myocardin Related
Philipp Kircher et al.
Science signaling, 8(402), ra112-ra112 (2015-11-12)
Megakaryoblastic leukemia 1 (MKL1) is a coactivator of serum response factor (SRF) that promotes the expression of genes associated with cell proliferation, motility, adhesion, and differentiation-processes that also involve dynamic cytoskeletal changes in the cell. MKL1 is inactive when bound
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