description
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product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CCATTTGCACTTCAGGGATTGCAAGACCAAAGTCAGCGGGGATGCACTGCAGCTCATGGCGGAGTTCCTGAGGATCTTCGTACTAGAGGCTGCTGTCCGTGGGGTCTGGCAGGCCCAGGCAGAAGACCTGGATGTTGTGGAAGTGGATCAGCTGGAGAAAGTGCTCCCTCAGCTGCTCCTGGACTTCTAGAGTTCCCTCCTGTGGCCTGCAAGGTCTAGTGAATCCACACCAGCATCAACTCCTGAGCTCTCCAGCTTCAGGAGGATGGGAAGATCCCAGCAGCTGTTACCTCCAAGAGTCCTTGCAAGACAGGTGCAGGGAAAGGTGAACCAGCCTGCCTCCAGACACAGCCCTCCTCCCGCCCCCAGCAGCCTTGCATTATAAATAAACCAGCTGCTGGCAGTGCTCCTTCTTGCCACCCTACA
Ensembl | mouse accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
mouse ... STRA13(20892), Stra13(20892)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Rui Ning et al.
Frontiers in pharmacology, 8, 866-866 (2017-12-14)
Inflammatory burden is a primary cellular event in many liver diseases, and the overall capacity of drug elimination is decreased. PXR (pregnane X receptor) and CAR (constitutive androstane receptor) are two master regulators of genes encoding drug-metabolizing enzymes and transporters.
Qiang Liu et al.
International journal of molecular medicine, 38(6), 1727-1733 (2016-11-15)
The functions of basic helix-loop-helix (bHLH) transcription factor-differentiated embryonic chondrocyte (DEC)1 (BHLHE40) and 2 (BHLHE41) are involved in various fields such as circadian rhythms, immune responses, cell proliferation, hypoxia reaction as well as malignant tumors. Previous findings showed that DEC served as apoptosis regulators
Yong-Sheng Teng et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(1), 1169-1181 (2020-01-10)
BHLHE40, a member of the basic helix-loop-helix transcription factor family, has been reported to play an important role in inflammatory diseases. However, the regulation and function of BHLHE40 in Helicobacter pylori (H pylori)-associated gastritis is unknown. We observed that gastric
Aarti Sethuraman et al.
Breast cancer research : BCR, 20(1), 117-117 (2018-10-05)
Metastasis is responsible for a significant number of breast cancer-related deaths. Hypoxia, a primary driving force of cancer metastasis, induces the expression of BHLHE40, a transcription regulator. This study aimed to elucidate the function of BHLHE40 in the metastatic process
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