描述
Powered by Eupheria Biotech
质量水平
产品线
MISSION®
形式
lyophilized powder
esiRNA cDNA靶序列
TTCTGCAAGCCCAAGAAGTTCACCACCATGATGGTCACACTCAACTGTCCTGAGCTACAGCCACCCACCAAGAAGAAAAGGGTCACACGCGTGAAGCAGTGCCGTTGCATATCCATCGACTTGGATTAAGTCAAAGCGGGCACATTCAGCCTGTCATAGCCATGCTGAGAGAGCCACACCCAAACCACCCGATTCCTACTTGGCTTAAACCTAGAGGCCAGAAGAACCAGCAGTTGCTTCCTGGCTGGAGGCTGCTTATGCATAGTGTATGCGCATGAGTGTGCATGGGTGCCTGTGGGTGTTTCCAAACACCAGCCGGAAACAGCCTTTGCTAGAAGGCACTTCCTGTTACTCTGCTTCAGATGGTCGGAAATGCCCACACCACTGGACCCAAACATCCACAGGGGCAGGGCTGTAGTTGGCTTTGTCATTGTGTTCCATGTGCCT
基因组数据库 |小鼠登记号
NCBI登记号
运输
ambient
储存温度
−20°C
基因信息
mouse ... GREM1(23892) , Grem1(23892)
相关类别
一般描述
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
法律信息
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Nam Ji Sung et al.
International journal of molecular sciences, 21(23) (2020-12-09)
Gremlin-1 (GREM1), one of the bone morphogenetic protein (BMP) antagonists, can directly bind to BMPs. GREM1 is involved in organogenesis, tissue differentiation, and organ fibrosis. Recently, numerous studies have reported the oncogenic role of GREM1 in cancer. However, the role
Gremlin-1 activates Akt/STAT3 signaling, which increases the glycolysis rate in breast cancer cells.
Na Hui Kim et al.
Biochemical and biophysical research communications, 533(4), 1378-1384 (2020-10-25)
Gremlin-1 (GREM1), one of the antagonists of bone morphogenetic proteins (BMPs), has recently been reported to be overexpressed in a variety of cancers including breast cancer. GREM1 is involved in tumor promotion, but little is known about its role in
Julie R Graham et al.
Journal of cellular biochemistry, 115(9), 1539-1548 (2014-03-19)
Fibrosis is a chronic disease characterized by an excessive deposition of scar tissue in the affected organs. A central mediator of this process is transforming growth factor-β (TGF-β), which stimulates the production of extracellular matrix proteins such as collagens. MicroRNAs
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