描述
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质量水平
产品线
MISSION®
表单
lyophilized powder
esiRNA cDNA靶序列
GCACATTGACTTTGGGGACTGCTTTGAGGTCGCTATGACCAGAGAGAAATTTCCAGAAAAGATTCCATTTAGACTAACAAGAATGTTGACCAATGCTATGGAGGTTACGGGTCTGGATGGCAACTACAGAACCACATGCCACACTGTGATGGAAGTGCTCCGAGAGCACAAGGACAGTGTCATGGCTGTGCTGGAAGCCTTTGTCTATGACCCGCTGCTCAACTGGAGGCTGATGGACACGAATACCAAAGGCAATAAGCGGTCCCGGACAAGGACAGACTCCTACTCTGCCGGCCAGTCAGTAGAAATTTTGGACGGTGTAGAACTTGGAGAACCAGCCCATAAGAAAGCAGGGACCACTGTGCCAGAATCCATCCATTCATTCATTGGAGACGGTTTGGTGAAACCAG
基因组数据库 |小鼠登记号
NCBI登记号
运输
ambient
储存温度
−20°C
基因信息
mouse ... Frap1(56717)
一般描述
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
法律信息
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Benjamin Frank et al.
Parasites & vectors, 8, 404-404 (2015-08-01)
Autophagy participates in innate immunity by eliminating intracellular pathogens. Consequently, numerous microorganisms have developed strategies to impair the autophagic machinery in phagocytes. In the current study, interactions between Leishmania major (L. m.) and the autophagic machinery of bone marrow-derived macrophages
Hana Schmeisser et al.
Autophagy, 9(5), 683-696 (2013-02-20)
Autophagy is an evolutionarily conserved cellular recycling mechanism that occurs at a basal level in all cells. It can be further induced by various stimuli including starvation, hypoxia, and treatment with cytokines such as IFNG/IFNγ and TGFB/TGFβ. Type I IFNs
Clare F Malone et al.
Cancer discovery, 4(9), 1062-1073 (2014-06-11)
NF1 encodes a RAS GTPase-activating protein. Accordingly, aberrant RAS activation underlies the pathogenesis of NF1-mutant cancers. Nevertheless, it is unclear which RAS pathway components represent optimal therapeutic targets. Here, we identify mTORC1 as the key PI3K effector in NF1-mutant nervous
Anupama Karnam et al.
Molecular immunology, 68(2 Pt A), 280-289 (2015-10-04)
Immune responses during fungal infections are predominately mediated by 5/15-lipoxygenases (LO)- or cyclooxygenase (COX)-2-catalysed bioactive eicosanoid metabolites like leukotrienes, lipoxins and prostaglandins. Although few host mediators of fungi-triggered eicosanoid production have been established, the molecular mechanism of expression and regulation
Chider Chen et al.
The Journal of experimental medicine, 212(1), 73-91 (2014-12-24)
Fibrillin-1 (FBN1) deficiency-induced systemic sclerosis is attributed to elevation of interleukin-4 (IL4) and TGF-β, but the mechanism underlying FBN1 deficiency-associated osteopenia is not fully understood. We show that bone marrow mesenchymal stem cells (BMMSCs) from FBN1-deficient (Fbn1(+/-)) mice exhibit decreased
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