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安全信息

EMU011931

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Lcp1

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About This Item

UNSPSC代码:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

质量水平

100

产品线

MISSION®

形式

lyophilized powder

esiRNA cDNA靶序列

AAGAGCGGACCTTCAGGAATTGGATGAACTCCCTGGGCGTTAACCCGCGCGTCAATCACTTGTACAGTGACTTATCGGATGCCTTAGTCATCTTCCAGCTCTATGAGAAGATCAAAGTCCCTGTTGATTGGAACAGAGTAAACAAGCCTCCATACCCCAAGCTGGGGGGCAATATGAAAAAGCTGGAGAACTGTAATTATGCAGTGGACCTGGGGAAGAATCAAGCTAAATTCTCCCTGGTTGGCATCGCAGGACAAGACCTCAATGAAGGAAACCGAACTCTCACGCTGGCATTGGTTTGGCAGCTCATGAGAAGGTACACACTGAATATCCTGGAAGATATCGGAGGTGGACAGAAGGTCAATGATGACATTATTGTCAACTGGGTGAATACGACCTTGAAGGAGGCACAGAAAAGCTCA

基因组数据库 |小鼠登记号

ENSMUSG00000021998

NCBI登记号

NM_008879

运输

ambient

储存温度

−20°C

基因信息

mouse ... LCP1(18826) , Lcp1(18826)

一般描述

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律信息

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Ping-Ping He et al.
Biochimie, 106, 81-90 (2014-08-26)
Accumulating evidence suggests that microRNA-590 (miR-590) has protective effects on cardiovascular diseases, but the mechanism is unknown. Interestingly, previous studies from our laboratory and others have shown that macrophage-derived lipoprotein lipase (LPL) might accelerate atherosclerosis by promoting lipid accumulation and
Majib Jan et al.
Biochemical and biophysical research communications, 462(1), 33-37 (2015-05-02)
In previous studies, we demonstrated that down-regulation of lipoprotein lipase in L6 muscle cells increased insulin-stimulated glucose uptake. In the current study, we used RNA interference technology to silence the LPL gene in L6 cells and generate a LPL-knock-down (LPL-KD)
Uri Rozovski et al.
Molecular cancer research : MCR, 13(5), 944-953 (2015-03-04)
While reviewing chronic lymphocytic leukemia (CLL) bone marrow slides, we identified cytoplasmic lipid vacuoles in CLL cells but not in normal B cells. Because lipoprotein lipase (LPL), which catalyzes hydrolysis of triglycerides into free fatty acids (FFA), is aberrantly expressed

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