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安全信息

EHU159091

Sigma-Aldrich

MISSION® esiRNA

targeting human GPR17

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About This Item

UNSPSC代码:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

质量水平

产品线

MISSION®

表单

lyophilized powder

esiRNA cDNA靶序列

GGGCTTGTGATGGCTACAATGGCTCCTAGACACTCAACGACTTCATCTGTGGCAGGGAGAGAGGAGGCCGGAAGAACAACCCCTGAACAATGGAGGCCTTTCTTTCCCGCTAGGCTCCCAGCCTCCTTCCCGCTACAGAATCGCTCATCGGCGAGGCTCAGCAGAAAGACCCTGAAGGCAGGCTGCAAATGACCCAGAAGAGGGACCTGGGAGTCCTGGTGGGGACGGGGAGGGAGTCTCAATACTCCTTTGCAGTGCAAGGTACTCTGAGTCCCCTCTGTAGTGCCTCTGCCAGACACACACTGCCTGAGTTGAAGAGACACAGGCCACACA

基因组数据库 |人类登记号

NCBI登记号

运输

ambient

储存温度

−20°C

基因信息

一般描述

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律信息

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

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Zhangfu Wang et al.
International immunopharmacology, 88, 106870-106870 (2020-08-18)
Osteoarthritis (OA) is a common joint disease affecting millions of elderly people worldwide. However, the mechanism of OA is complicated and remains poorly understood. Thus, a safe and effective therapeutic strategy has yet to be developed. G protein-coupled receptor 17
Simona Cosentino et al.
Journal of cellular and molecular medicine, 18(9), 1785-1796 (2014-06-10)
GPR17 is a G(i) -coupled dual receptor activated by uracil-nucleotides and cysteinyl-leukotrienes. These mediators are massively released into hypoxic tissues. In the normal heart, GPR17 expression has been reported. By contrast, its role in myocardial ischaemia has not yet been
Bing Zhao et al.
International journal of molecular medicine, 42(5), 2750-2762 (2018-09-19)
GPR17 is a G (i)-coupled dual receptor, linked to P2Y and CysLT receptors stimulated by uracil nucleotides and cysteinyl leukotrienes, respectively. Recent evidence has demonstrated that GPR17 inhibition ameliorates the progression of cerebral ischemic injury by regulating neuronal death and

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