产品名称
MISSION® esiRNA, targeting human LRWD1
description
Powered by Eupheria Biotech
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
ACCTGTCAGGATTGGAGCTGCTTTCCGAGCACCTGGACCCCAAACTCCTGTGCCGCCTGACGCAGCTGCAGGAGCTTGACCTGTCTAACAACCACCTGGAGACGCTGCCGGACAACCTGGGCCTGTCCCACCTGCGTGTCCTCCGCTGCGCCAACAACCAGCTGGGGGATGTTACTGCCTTGTGCCAGTTCCCCAAGCTCGAGGAACTCAGCCTGGAGGGCAACCCCTTCCTGACGGTCAATGACAACCTGAAAGTCTCCTTTCTCCTGCCCACGCTCCGTAAGGTCAATGGCAAGGATGCGTCCTCAACTTACTCTCAGGTGGAGAACCTGAATCGGGAGCTGACCAGCAGGGTCACAGCTCACTGGGAGAAGTTCATGGCCACACTGGGTCCTGAAGAGGAGGCTGAGAAGGCCCAGGCGGACTTTGTGAAGTCGGCTGTCAGGGATGTCCGCTACGGGCCCGAGTCCCTCAGCGAGTTCAC
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
human ... LRWD1(222229), LRWD1(222229)
General description
MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Julien Brustel et al.
The EMBO journal, 36(18), 2726-2741 (2017-08-06)
Among other targets, the protein lysine methyltransferase PR-Set7 induces histone H4 lysine 20 monomethylation (H4K20me1), which is the substrate for further methylation by the Suv4-20h methyltransferase. Although these enzymes have been implicated in control of replication origins, the specific contribution
Satish Sati et al.
Molecular cell, 78(3), 522-538 (2020-03-30)
To understand the role of the extensive senescence-associated 3D genome reorganization, we generated genome-wide chromatin interaction maps, epigenome, replication-timing, whole-genome bisulfite sequencing, and gene expression profiles from cells entering replicative senescence (RS) or upon oncogene-induced senescence (OIS). We identify senescence-associated heterochromatin
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