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Merck
CN
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主要文件

安全信息

EHU123751

Sigma-Aldrich

MISSION® esiRNA

targeting human CLDN5

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选择尺寸

25 G
CN¥223.12
100 G
CN¥582.04

CN¥223.12

预计发货时间June 25, 2025详情

所有图片(1)

选择尺寸

变更视图
25 G
CN¥223.12
100 G
CN¥582.04

About This Item

UNSPSC代码:
41105324
NACRES:
NA.51

CN¥223.12

预计发货时间June 25, 2025详情

描述

Powered by Eupheria Biotech

产品线

MISSION®

表单

lyophilized powder

esiRNA cDNA靶序列

CAGGCTCCTCGGAACGTCCGGCTCTGCGCCCCGACGCGGCTCCTGGATCCGCTCCTGCCTGCGCCCGCAGCTGACCTTCTCCTGCCACTAGCCCGGCCCTGCCCTTAACAGACGGAATGAAGTTTCCTTTTCTGTGCGCGGCGCTGTTTCCATAGGCAGAGCGGGTGTCAGACTGAGGATTTCGCTTCCCCTCCAAGACGCTGGGGGTCTTGGCTGCTGCCTTACTTCCCAGAGGCTCCTGCTGACTTCGGAGGGGCGGATGCAGAGCCCAGGGCCCCCACCGGAAGATGTGTACAGCTGGTCTTTACTCCATCGGCAGGGCCCGAGCCCAGGGACCAGTGACTTGGCCTGGACCTCCCGGTCTCACTCCAGCATCTCCCCAGGCAAGGCTTGTGGGCACCGGAGCTTGAGAGAGGGCGGGAGTGGGAAGGCTAAGAATC

基因组数据库 |人类登记号

ENSG00000184113

NCBI登记号

NM_001130861

运输

ambient

储存温度

−20°C

基因信息

human ... CLDN5(7122) , CLDN5(7122)

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此商品
A77997V900286736023
2-氨基嘧啶 97%

A78608

2-氨基嘧啶

2-氨基吡啶 99%

A77997

2-氨基吡啶

2-氨基嘧啶 Vetec™, reagent grade, 97%

V900286

2-氨基嘧啶

3-Amino-4-iodopyridine 97%

736023

3-Amino-4-iodopyridine

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

mp

122-126 °C (lit.)

mp

54-58 °C (lit.)

mp

122-126 °C (lit.)

mp

65-70 °C

form

powder

form

crystals

form

-

form

solid

一般描述

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律信息

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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    Yanan Jia et al.
    American journal of translational research, 11(9), 5546-5559 (2019-10-22)
    The combination of anti-angiogenesis and chemotherapy can significantly prolong the survival period of patients with non-squamous non-small cell lung cancer (NSCLC). But drug resistance will inevitably occur, thereby causing increased tumor invasion and metastasis. Claudin-5 (CLDN5) is a protein member
    Christine M Gross et al.
    American journal of respiratory cell and molecular biology, 58(5), 614-624 (2017-11-09)
    One of the early events in the progression of LPS-mediated acute lung injury in mice is the disruption of the pulmonary endothelial barrier resulting in lung edema. However, the molecular mechanisms by which the endothelial barrier becomes compromised remain unresolved.
    Natalie Hudson et al.
    JCI insight, 4(15) (2019-08-09)
    Age-related macular degeneration (AMD) is the leading cause of central retinal vision loss worldwide, with an estimated 1 in 10 people over the age of 55 showing early signs of the condition. There are currently no forms of therapy available

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