描述
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质量水平
产品线
MISSION®
形式
lyophilized powder
esiRNA cDNA靶序列
TCAGGCTATTAAAGCCCTTCCTAGCCTTAAAGAGCTAGGATTTCATAGTAATTCTATTTCTGTTATCCCTGATGGAGCATTTGATGGTAATCCACTCTTAAGAACTATACATTTGTATGATAATCCTCTGTCTTTTGTGGGGAACTCAGCATTTCACAATTTATCTGATCTTCATTCCCTAGTCATTCGTGGTGCAAGCATGGTGCAGCAGTTCCCCAATCTTACAGGAACTGTCCACCTGGAAAGTCTGACTTTGACAGGTACAAAGATAAGCAGCATACCTAATAATTTGTGTCAAGAACAAAAGATGCTTAGGACTTTGGACTTGTCTTACAATAATATAAGAGACCTTCCAAGTTTTAATGGTTGCCATGCTCTGGAAGAAATTTCTTTACAGCGTAATCAAATCTACCAAATAAAGGAAGGCACCTTTCAAGG
基因组数据库 |人类登记号
NCBI登记号
运输
ambient
储存温度
−20°C
基因信息
human ... LGR4(55366) , LGR4(55366)
相关类别
一般描述
MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
法律信息
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Basit Salik et al.
Cancer cell, 38(2), 263-278 (2020-06-20)
Signals driving aberrant self-renewal in the heterogeneous leukemia stem cell (LSC) pool determine aggressiveness of acute myeloid leukemia (AML). We report that a positive modulator of canonical WNT signaling pathway, RSPO-LGR4, upregulates key self-renewal genes and is essential for LSC
Liping Zhang et al.
EBioMedicine, 44, 275-288 (2019-05-18)
R-spondins (Rspo) and leucine-rich repeat-containing G-protein-coupled receptors (LGR) play important roles in development, stem cells survival, and tumorigenicity by activating Wnt signaling pathway. Whether R-spondins-LGR signaling affects the progression of squamous cell carcinoma (SCC) remain unknown. This study aims to
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