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Merck
CN

EHU063501

MISSION® esiRNA

targeting human CAV3

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NACRES:
NA.51
UNSPSC Code:
41105324

主要文件

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产品名称

MISSION® esiRNA, targeting human CAV3

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GAGCACACGGTGTAGGGAAGCCAGAAAGAAAAGACGGCCCAGCCACAGAAGCACAATGGCCCTTCGCTCTCCCCCAGCCCCACCATGATGCCCCCATGCCTGGGCGTGGGGGAAGATCATTTGCCAAGAGGCAGCTACTGCAAGTCTTTGCGTTCACTTGTACTGTAACAACATAAACCAGCACGCGGTTCCCACCCGGGGCCAACCTCTCCACGCGCACTCAGGAAAGTGACCAGTGACCACTGGCGTTAGGAAGGTGGCTCCAGTAAAGGGTTTTGGCTGCATTTGGGGAATGCTGCATTTTGTTCGTGCCTGTAAGATTGGTTTGTGTCCTGACCAGCTCCAAAAATATACTTCACTGCCCTGAAAAACAGACACAGGGAGAGTTGGTTGTCTCTTCACTTGGCCAAATGTAAGTGAAGAACAGAGTCTTTTTCTTCTTCGGATTCTATTGTTTGCTGGAACCGTACA

Ensembl | human accession no.

ENSG00000182533

NCBI accession no.

NM_033337

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

human ... CAV3(859), CAV3(859)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Lot/Batch Number
GRR

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Melissa Dewulf et al.
Nature communications, 10(1), 1974-1974 (2019-05-01)
Caveolin-3 is the major structural protein of caveolae in muscle. Mutations in the CAV3 gene cause different types of myopathies with altered membrane integrity and repair, expression of muscle proteins, and regulation of signaling pathways. We show here that myotubes
Shaoqing Lei et al.
Oxidative medicine and cellular longevity, 2019, 9836302-9836302 (2019-10-05)
Diabetic hearts are more vulnerable to ischemia/reperfusion (I/R) injury and less responsive to remifentanil preconditioning (RPC), but the underlying mechanisms are incompletely understood. Caveolin-3 (Cav-3), the dominant isoform of cardiomyocyte caveolae, is reduced in diabetic hearts in which oxidative stress

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