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安全信息

EHU060091

Sigma-Aldrich

MISSION® esiRNA

targeting human SYVN1

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About This Item

UNSPSC代码:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

质量水平

100

产品线

MISSION®

形式

lyophilized powder

esiRNA cDNA靶序列

GCTGGAGGCAAGCTATGAACTTGCTCGCTGGCCCACCCCTAAGACTGGTACCCATTTCCTTTTCTTACCCTGATCTCCCCAGAAGCCTCTTGTGGTGGTGGCTGTGCCCCCTATGCCCTGTGGCATTTCTGCGTCTTACTGGCAACCACACAACTCAGGGAAAGGAATGCCTGGGAGTGGGGGTGCAGGCGGGCAGCACTGAGGGACCCTGCCCCGCCCCTCCCCCCAGGCCCCTTTCCTCTGCAGCTTCTCAAGTGAGACTGACCTGTCTCACCCAGCAGCCACTGCCCAGCCGCACTCCAGGCAAGGGCCAGTGCGCCTGCTCCTGACCACTGCAATCCCAGCGCCCAAGGAAGGCCACTTCTCAACTGGCAGAACTTCTGAAGTTTAGAATTGGAATTACTTCCTTACTAGTGTCTTTTGGCTTAAATTTTGTCTTTTGAAGTTGAATGCTTAATCCCGGGAAAGAGGAACAGGAGTGCCAGA

基因组数据库 |人类登记号

ENSG00000162298

NCBI登记号

NM_172230

运输

ambient

储存温度

−20°C

基因信息

human ... SYVN1(84447) , SYVN1(84447)

一般描述

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律信息

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Yosuke Osaki et al.
Biochemical and biophysical research communications, 514(1), 217-223 (2019-04-29)
Mucopolysaccharidosis type II (MPS II) is one of the most common mucopolysaccharidoses, which is caused by mutation of the gene encoding iduronate 2-sulfatase (IDS). The loss of function of IDS leads to the accumulation of heparan sulfate and dermatan sulfate
Marioara Chiritoiu et al.
International journal of molecular sciences, 21(10) (2020-05-20)
Endoplasmic reticulum (ER)-associated degradation (ERAD) is the main mechanism of targeting ER proteins for degradation to maintain homeostasis, and perturbations of ERAD lead to pathological conditions. ER-degradation enhancing α-mannosidase-like (EDEM1) was proposed to extract terminally misfolded proteins from the calnexin

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