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Merck
CN

EHU049221

MISSION® esiRNA

targeting human CDCP1

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关于此项目

NACRES:
NA.51
UNSPSC Code:
41105324

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description

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product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCCAACAATGGGGATGTAAGCAGCAAGGACACAGACATTCCCTTACTGAACACTCAGGAGCCCATGGAGCCAGCAGAATAACTTGATCCATTCCAGACGCTTTGCTGAGTTTCATAAAGCAGGGCACTGAGACACCCGTCCGTGTTCCTAACCAGAAATCCTAAAGAAGAGGAATTATACAGAAGGAACAGCAGGAGGTTTTCCTGGACACCGCCAACTTCACATTGCTCAGTGGACTCATTCTAAGGGCAAGACATTGAAAATGATGAATTCCAATCTGGATACAGTCATGACAGCTCATGTGCTCCTCAACTTAGGCTGTGCGGTTAGCCAGCCTGTAATGAGAGGAGAGAGGCCTGAGTCACCTAGCATAGGGTTGCAGCAAGCCCTGGATTCAGAGTG

Ensembl | human accession no.

ENSG00000163814

NCBI accession no.

NM_022842

shipped in

ambient

storage temp.

−20°C

Quality Level

100

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Nina Noskovičová et al.
American journal of physiology. Lung cellular and molecular physiology, 314(5), L695-L707 (2018-01-20)
Fibroblasts are thought to be the prime cell type for producing and secreting extracellular matrix (ECM) proteins in the connective tissue. The profibrotic cytokine transforming growth factor-β1 (TGF-β1) activates and transdifferentiates fibroblasts into α-smooth muscle actin (α-SMA)-expressing myofibroblasts, which exhibit
Lijun Huang et al.
Cancer management and research, 12, 3759-3769 (2020-06-18)
Emerging evidence have revealed significant contributions of CUB domain-containing protein-1 (CDCP1) in tumorigenesis, including colon, renal, ovarian, pancreatic, prostate and breast cancers. However, the roles of CDCP1 in cervical cancer (CC) still remain elusive. Quantitative reverse transcription polymerase chain reaction

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