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EHU001391

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA
Price: 3096.05 CNY
Availability: InStock

targeting human TMEM131

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20 μG

¥3,096.05

50 μG

¥5,521.27

¥3,096.05

预计发货时间2025年6月04日详情

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变更视图

20 μG

¥3,096.05

50 μG

¥5,521.27

About This Item

UNSPSC代码:

41105324

NACRES:

NA.51

¥3,096.05

预计发货时间2025年6月04日详情

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此商品	EHU080671	EHU009761	EHU029791
EHU001391 MISSION^® esiRNA	EHU080671 MISSION^® esiRNA	EHU009761 MISSION^® esiRNA	EHU029791 MISSION^® esiRNA
Gene Information human ... TMEM131(23505), TMEM131(23505)	Gene Information human ... TMEM130(222865), TMEM130(222865)	Gene Information human ... TMEM133(143872), TMEM133(83935)	Gene Information human ... TMEM134(80194), TMEM134(80194)
product line MISSION^®	product line MISSION^®	product line MISSION^®	product line MISSION^®
esiRNA cDNA target sequence GGTCCAAGGACAAGGAACAACTGAGAACTTGAGGGTGGCAGGCAAGCTTCCAGGTCCAGGAAGCTCCTTACGCTTTAAAATCACGGAAGCATTGTTAAAAGATTGTACAGATAGTTTAAAACTAAGAGAACCAAATTTCACATTGAAAAGAACATTTAAGGTAGAGAATACAGGACAACTTCAAATTCACATAGAAACCATTGAAATCAGTGGATACTCATGTGAAGGATATGGCTTTAAAGTTGTTAATTGTCAAGAGTTTACTCTAAGTGCCAATGCTTCTAGAGATATAATCATATTGTTTACTCCTGATTTTACAGCTTCTAGAGTTATTCGGGAACTGAAGTTTATAACAACCAGTGGCTCTGAGTTTGTATTTATATTGAATGCATCCCTTCCTTACCATATGTTAGCAACCTGTGCAGAAGCCCTACCCAGACCT	esiRNA cDNA target sequence GATGGGCACACTCACAGAGAGAAGTGTGCATGTACACACACCACACACACACACACACACACACACACACACACACACAGAAATATAAACACATGCGTCACATGGGCATTTCAGATGATCAGCTCTGTATCTGGTTAAGTCGGTTGCTGGGATGCACCCTGCACTAGAGCTGAAAGGAAATTTGACCTCCAAGCAGCCCTGACAGGTTCTGGGCCCGGGCCCTCCCTTTGTGCTTTGTCTCTGCAGTTCTTGCGCCCTTTATAAGGCCATCCTAGTCCCTGCTGGCTGGCAGGGGGCTGGATGGGGGGCAGGACTAATACTGAGTGATTGCAGAGTGCTTTATAAATATCACCTTATTTTATCGAAACCCATCTGTGAAACTTTCACTGAGGAAAAGGCCTTGC	esiRNA cDNA target sequence CCTCAGAGCTTTGCCTCAAGCAATTTCAAATTGTAGTGATACCTTAAATCATGTATTCAGGATGCCTTCTTTAGCATTTAGAACCCCAACTAGACTTATACTTTGACTAAAGTCAGAGGCAGACCAATTTAGGGAACAGATTTTGTTCTTTGCTTTTATGATACATTTGTAACTCACAGCTGTTAGCATGACCTCACATCACTGCGTAGGACCCGGAAATCACATCTCCTGGTCAGGTCACGAAAAAGAACACAGGCTTGACTATTGTCCAGAAGTTACTTTCCCCTTGACTAAAGGTTTCCCCTTAGGGTACACATTGCTATTTAACTTTGCCTCCTACCCTTTTTTGTTACCTTCCAAAATCAAGACACTTTTAAGAAACAAAGATAGTTTTCTGAACATTCTGTGTCCTGCCTGTCTCCTGTTGATTCGCA	esiRNA cDNA target sequence ATTCCAGCCGAACTTCCATCCGCAGCTCCCAGTGGTCCTTCAGCACCATCAGCAGCAGCACCCAGCGCTCCTACAACACCTGCTGCAGCTGGACCCAACACCCTTTGATCCAGAAGAACCGCCGAGTGGTGCTGGCCTCCTTCCTGCTCCTGCTGCTGGGGCTGGTGCTGATCCTGGTCGGCGTGGGACTGGAGGCGACCCCCTCTCCAGGTGTCTCCAGCGCCATCTTCTTCGTGCCGGGCTTCCTGTTGTTGGTGCCTGGAGTCTATCACGTGATCTTCATCTACTGCGCGGTCAAGGGCCACCGGGGCTTCCAGTTCTTCTACCTGCCCTACTTCGAGAAGTGATCGCGGCGCAGCGTGGACCCCTTGCGCCCATGGGGGCGCCCCTCTTGCCCTGTTCCGTTCCCCTCATCTCAAGGGAAGAGGCCCTCCAGGACCCTCGAAACCCCAGCCCCTAGGGAGTTTGCTCAGGAAGTTCGG
form lyophilized powder	form lyophilized powder	form lyophilized powder	form lyophilized powder
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

一般描述

MISSION^® shRNA是核糖核酸内切酶制备的siRNA。它们是靶向相同mRNA序列的siRNA异质混合物。这些多重沉默触发（multiple silencing trigger）导致高度特异性的、有效的基因沉默。

如需其他详细信息并查看所有可用的esiRNA选项，请访问SigmaAldrich.com/esiRNA。

法律信息

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis.

Karl E Carlström et al.

Nature communications, 11(1), 4071-4071 (2020-08-15)

Arrest of oligodendrocyte (OL) differentiation and remyelination following myelin damage in multiple sclerosis (MS) is associated with neurodegeneration and clinical worsening. We show that Glutathione S-transferase 4α (Gsta4) is highly expressed during adult OL differentiation and that Gsta4 loss impairs

Synergistic effect of siRNA-mediated silencing of TGF-β R1 and TGF-β R2 genes on the proliferation and apoptosis of penile urethral epithelial cells in hypospadiac male rats.

Chao Wang et al.

Journal of cellular biochemistry, 119(2), 1646-1658 (2017-08-05)

The study elucidated the effects associated with silencing growth factor-β R1 (TGF-β R1) and TGF-β R2 genes on the proliferation and apoptosis of penile urethral epithelial cells (UECs) in hypospadiac male rats. Seventy-five male rats were distributed into the normal

Induction of cystathionine gamma-lyase expression and metallothionein-1 S-sulfhydration alleviate cadmium-induced cell death in myoblast cells.

Yanjie Zhang et al.

Ecotoxicology and environmental safety, 179, 222-231 (2019-05-03)

Hydrogen sulfide (H2S), a multifunctional gasotransmitter, participates in a wide range of cellular signal transduction and pathophysiological processes. Cystathionine gamma-lyase (CSE) acts as a major H2S-generating enzyme in peripheral organs and tissues. As a cysteine-rich and heavy metal-binding protein, metallothionein-1

Golgi Stress Response, Hydrogen Sulfide Metabolism, and Intracellular Calcium Homeostasis.

Yanjie Zhang et al.

Antioxidants & redox signaling, 32(9), 583-601 (2019-12-25)

Aims: The physiological and pathological importance of hydrogen sulfide (H2S) as a novel gasotransmitter has been widely recognized. Cystathionine

A novel Fer/FerT targeting compound selectively evokes metabolic stress and necrotic death in malignant cells.

Yoav Elkis et al.

Nature communications, 8(1), 940-940 (2017-10-19)

Disruption of the reprogrammed energy management system of malignant cells is a prioritized goal of targeted cancer therapy. Two regulators of this system are the Fer kinase, and its cancer cell specific variant, FerT, both residing in subcellular compartments including

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安全信息

MISSION^® esiRNA

targeting human TMEM131

选择尺寸