质量水平
检测方案
≥99.5% (titration)
形式
powder
pH值（酸碱度）
7.3-8.7
有效pH范围
7.3-8.7
pKa (25 °C)
8.0
pKa
8
mp
237-239 °C (lit.)
溶解性
H2O: 25 g + 50 mL, clear, colorless
λmax
A290 at ≤0.1 (C=33% w/w)
应用
diagnostic assay manufacturing
SMILES字符串
OCCN1CCN(CCCS(O)(=O)=O)CC1
InChI
1S/C9H20N2O4S/c12-8-7-11-5-3-10(4-6-11)2-1-9-16(13,14)15/h12H,1-9H2,(H,13,14,15)
InChI key
OWXMKDGYPWMGEB-UHFFFAOYSA-N
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应用
EPPS 已用于：
- 验证 pH 变化对中肠后部（PMG）内容物和中肠前部（AMG）组织匀浆蛋白水解活性的影响
- 制备染色脱色液以去除染色强烈的凝胶片
- 制备用于凝胶内酶解的消化缓冲液
- 重悬酶解后的肽，用于处理脑源性细胞外囊泡（EV）蛋白和 16 倍同量异序串联质量标签（TMT）肽标记
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Bernhard Sissolak et al.
Journal of industrial microbiology & biotechnology, 46(8), 1167-1178 (2019-06-09)
Recombinant monoclonal antibodies are predominantly produced in mammalian cell culture bioprocesses. Post-translational modifications affect the micro-heterogeneity of the product and thereby influence important quality attributes, such as stability, solubility, pharmacodynamics and pharmacokinetics. The analysis of the surface charge distribution of
YoungSoo Kim et al.
Science advances, 5(4), eaav1388-eaav1388 (2019-04-20)
Detection of amyloid-β (Aβ) aggregates contributes to the diagnosis of Alzheimer disease (AD). Plasma Aβ is deemed a less invasive and more accessible hallmark of AD, as Aβ can penetrate blood-brain barriers. However, correlations between biofluidic Aβ concentrations and AD
Yang You et al.
Journal of extracellular vesicles, 11(1), e12183-e12183 (2022-01-15)
In neurodegenerative diseases, extracellular vesicles (EVs) transfer pathogenic molecules and are consequently involved in disease progression. We have investigated the proteomic profiles of EVs that were isolated from four different human-induced pluripotent stem cell-derived neural cell types (excitatory neurons, astrocytes
Bianca Santos Henriques et al.
Frontiers in physiology, 11, 509310-509310 (2021-02-02)
Rhodnius prolixus is one important vector for the parasite Trypanosoma cruzi in Latin America, where Chagas disease is a significant health issue. Although R. prolixus is a model for investigations of vector-parasite interaction and transmission, not much has been done
Heeseon An et al.
Nature, 583(7815), 303-309 (2020-07-03)
Mammalian cells reorganize their proteomes in response to nutrient stress through translational suppression and degradative mechanisms using the proteasome and autophagy systems1,2. Ribosomes are central targets of this response, as they are responsible for translation and subject to lysosomal turnover
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