E8625
毒扁豆碱 半硫酸盐
别名:
伊色林 半硫酸盐
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关于此项目
经验公式（希尔记法）:
C15H21N3O2 · 0.5H2SO4
化学文摘社编号:
分子量:
324.39
EC Number:
200-585-4
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
3828413
MDL number:
InChI key
YYBNDIVPHIWTPK-KYJQVDHRSA-N
InChI
1S/2C15H21N3O2.H2O4S/c2*1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2;1-5(2,3)4/h2*5-6,9,13H,7-8H2,1-4H3,(H,16,19);(H2,1,2,3,4)/t2*13-,15+;/m11./s1
SMILES string
OS(O)(=O)=O.CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1.CNC(=O)Oc4ccc5N(C)[C@H]6N(C)CC[C@@]6(C)c5c4
storage temp.
2-8°C
Biochem/physiol Actions
乙酰胆碱酯酶抑制剂越过血脑屏障并与乙酰胆碱酯酶形成缓慢降解的氨基甲酰酶络合物。
可越过血脑屏障的乙酰胆碱酯酶抑制剂。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 1 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Vikas Trivedi et al.
Biomedical chromatography : BMC, 34(3), e4777-e4777 (2019-12-12)
The article describes a systematic study to overcome the matrix effect during chromatographic analysis of gemfibrozil, rivastigmine, telmisartan and tacrolimus from biological fluids using LC-ESI-MS/MS. All four methods were thoroughly developed by the appropriate choice of analytical column, elution mode
Y H Lu et al.
Journal of insect science (Online), 13, 9-9 (2013-07-25)
The aphids Sitobion avenae (Fabricius) and Rhopalosiphum padi (Linnaeus) (Hemiptera: Aphidiae) are serious pests on grain crops and usually coexist on late period of wheat growth in China. Bioassays showed that R. padi was more susceptible than S. avenae to
Anderson Ribeiro-Carvalho et al.
PloS one, 15(10), e0239017-e0239017 (2020-10-03)
Organophosphates are among the most used pesticides. Particularly, chlorpyrifos (CPF) is responsible for a number of deleterious effects on brain development, which may program behavioral changes later in life. Here, we investigated whether a regimen of early low level CPF
Jan-Oliver Hollnagel et al.
iScience, 23(7), 101316-101316 (2020-07-13)
Lactate shuttled from blood, astrocytes, and/or oligodendrocytes may serve as the major glucose alternative in brain energy metabolism. However, its effectiveness in fueling neuronal information processing underlying complex cortex functions like perception and memory is unclear. We show that sole
Bruno Nunes et al.
Environmental science and pollution research international, 24(13), 12155-12167 (2017-03-30)
Biomonitoring of chemical contamination requires the use of well-established and validated tools, including biochemical markers that can be potentially affected by exposure to important environmental toxicants. Cholinesterases (ChEs) are present in a large number of species and have been successfully
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