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InChI
1S/C6H20N2O12P4.H3N/c9-21(10,11)3-7(4-22(12,13)14)1-2-8(5-23(15,16)17)6-24(18,19)20;/h1-6H2,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20);1H3
InChI key
STNSYZSNIYTNMI-UHFFFAOYSA-N
应用
Used as a complex with radioactive samarium as a radiopharmaceutical in cancer research. Corrosion inhibitor.
生化/生理作用
EDTMP is nitrogenous, polyphosphonic acid chelator that complexes with various metal ions.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
13 - Non Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
M F Desrosiers et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 44(1-2), 459-463 (1993-01-01)
Therapeutic and palliative uses of bone-seeking radiopharmaceuticals are undergoing clinical trials for human subjects. Radiation dosimetry for these applications is based on the Medical Internal Radiation Dosimetry (MIRD) schema. An experimental method for dosimetry of bone tissue based on electron
Stefan Toegel et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 68(2), 406-412 (2007-07-06)
The present study aimed to develop convenient preparation and quality control protocols for [(68)Ga]-EDTMP, a potential radiotracer for skeletal PET imaging. Furthermore, bone binding characteristics with special focus on the influence of carrier addition were evaluated. No-carrier-added (nca), carrier-added and
Y Tanaka et al.
Shigaku = Odontology; journal of Nihon Dental College, 78(3), 575-591 (1990-10-01)
Dose dependent effects of EDTPO on morphology and mineralization of hard tissues as well as calcium (Ca), inorganic phosphorus (IP) and alkaline phosphatase (ALP) levels in serum were examined in growing rats. Five groups of male S.D. rats weighing 110-120g
G J Beyer et al.
Nuclear medicine and biology, 24(5), 367-372 (1997-07-01)
High-resolution gamma spectroscopy was applied to measure simultaneously the biodistribution of carrier-free radionuclides of several lanthanides (141Ce, 145Sm, 149Gd, 167Tm) and 225Ac in tumor-bearing nude mice. Mixtures of the radiotracers were injected in solutions containing different concentrations of EDTMP (ethylenediaminetetramethylenephosphonic
M Láznícek et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 45(9), 949-953 (1994-09-01)
The pharmacokinetics and elimination of EDTMP chelates with different radionuclides (99mTc, 111In and 153Sm) has been investigated in rats. The biodistribution of the complexes under study was similar and two main processes, namely bone uptake and the elimination of glomerular
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