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InChI
1S/C6H20N2O12P4.H3N/c9-21(10,11)3-7(4-22(12,13)14)1-2-8(5-23(15,16)17)6-24(18,19)20;/h1-6H2,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20);1H3
InChI key
STNSYZSNIYTNMI-UHFFFAOYSA-N
应用
Used as a complex with radioactive samarium as a radiopharmaceutical in cancer research. Corrosion inhibitor.
生化/生理作用
EDTMP is nitrogenous, polyphosphonic acid chelator that complexes with various metal ions.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
13 - Non Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
J E Bayouth et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 35(1), 63-69 (1994-01-01)
Palliation of bone pain in patients with cancer metastatic to bone is being evaluated in several cancer centers by the administration of the bone-seeking phosphonate ethylenediaminetetramethylenephosphonic acid (EDTMP) chelated with the beta particle-emitting radionuclide 153Sm. In this study, 153Sm-EDTMP was
Radionuclide targeting of bone metastases: which efficacy?
S Leyvraz et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 8(9), 1598-1599 (1990-09-01)
Sabyasachi Sarkar et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 821(1), 81-87 (2005-05-28)
A matrix developed from N,N,N',N'-ethylenediaminetetramethylenephosphonic acid-modified zirconia beads (further referred to as r_PEZ); 25-38 microm in diameter and with a pore size of 22+/-3 nm, was utilized for the separation of immunoglobulins (Igs). r_PEZ has been shown to bind to
K Schomäcker et al.
Nuklearmedizin. Nuclear medicine, 32(1), 23-26 (1993-02-01)
It is well known that after application of radioactive complexes for tumour diagnosis or therapy, such as 67Ga-citrate or radiolanthanide complexes (167Tm- or 169Yb-nitrilotriacetate, -citrate, -alpha-hydroxyisobutyrate, 90Y-citrate, etc.) activity is accumulated not only in the tumour but also in other
A M Clausen et al.
Analytical chemistry, 70(2), 378-385 (1998-02-05)
Zirconium dioxide (zirconia) has a great affinity for inorganic and organic phosphate. Previous work from this laboratory demonstrated the utility of phosphate-modified microparticulate zirconia as a support for protein separations. We have extended this investigation to include the study of
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