InChI key
DPUYCSDGMSDKKV-MKBYFEBXSA-N
InChI
1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1
biological source
human aorta
form
lyophilized powder
technique(s)
cell culture | mammalian: suitable
impurities
salt, free
UniProt accession no.
storage temp.
2-8°C
Quality Level
Gene Information
human ... ELN(2006)
Biochem/physiol Actions
已报告梭状芽孢杆菌胶原酶抑制剂
弹性蛋白，连同原纤维蛋白，负责皮肤和动脉的弹性特性。已报告梭状芽孢杆菌胶原酶抑制剂。
Preparation Note
采用Partrige等人的方法从E6777制备。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
高风险级别生物产品--人源产品
此项目有
E H Sage et al.
Advances in experimental medicine and biology, 79, 291-312 (1977-01-01)
The aortae of a number of vertebrates and invertebrates were tested for the presence of elastin to determine when this protein first appears phylogenetically. Using several criteria, including amino acid composition, presence of desmosines, and histological characteristics, we found that
Jinzhi Li et al.
BMC cancer, 20(1), 217-217 (2020-03-17)
Colorectal cancer (CRC) is the most common cancer and a leading cause of death worldwide. Extracellular matrix (ECM) proteins regulate tumor growth and development in CRC. Elastin (ELN) is a component of ECM proteins involved in the tumor microenvironment. However
Hui Li et al.
Journal of anatomy, 236(1), 171-179 (2019-08-31)
Distinguishing arteries from veins in vivo has a great significance in clinical practices and preclinical studies. Optical imaging methods such as two-photon microscopy can provide high-resolution morphological information of tissue and are therefore extremely suitable for imaging small blood vessels.
The chemistry of connective tissues. 2. Soluble proteins derived from partial hydrolysis of elastin.
S M PARTRIDGE et al.
The Biochemical journal, 61(1), 11-21 (1955-09-01)
Aleksandra Kuzan et al.
Folia histochemica et cytobiologica, 59(1), 8-21 (2021-02-10)
Extracellular matrix (ECM) proteins have been associated with atherosclerotic complications, such as plaque rupture, calcification and aneurysm. It is not clear what role different types of collagen play in the pathomechanism of atherosclerosis. The aim of the study was to
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