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Merck
CN

E5391

乙二胺四乙酸 四钠盐 水合物

≥99.0%

别名:

EDTA 四钠盐, 乙二胺四乙酸四钠盐 水合物, 依地酸

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关于此项目

线性分子式:
(NaOOCCH2)2NCH2CH2N(CH2COONa)2 · xH2O
化学文摘社编号:
分子量:
380.17 (anhydrous basis)
UNSPSC Code:
12352204
NACRES:
NA.83
PubChem Substance ID:
EC Number:
200-573-9
Beilstein/REAXYS Number:
3861753
MDL number:
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产品名称

乙二胺四乙酸 四钠盐 水合物, ≥99.0%

InChI key

GXFFSKMBMYHTAE-UHFFFAOYSA-J

InChI

1S/C10H16N2O8.4Na.H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;1H2/q;4*+1;/p-4

SMILES string

O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O

biological source

synthetic (organic)

assay

≥99.0%

form

powder

technique(s)

ligand binding assay: suitable

impurities

Insoluble matter, passes filter test

pH

11.0-12.0 (0.1 M in H2O)

solubility

H2O: 0.1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.01%

cation traces

Al: ≤0.001%
As: ≤0.0001%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: <0.001%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
Li: ≤0.0005%
Mg: ≤0.0005%
Mn: ≤0.0005%
Mo: ≤0.0005%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.0005%
Zn: ≤0.0005%

absorption

≤0.06 at 280 in H2O at 0.1 M
≤1.5 at 260 in H2O at 0.1 M

application(s)

sample preparation

storage temp.

room temp

Quality Level

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Application

EDTA 为金属蛋白酶抑制剂,有效浓度为 1-10 mM。EDTA 可用作金属蛋白酶活性中心锌离子的螯合剂,并且还可抑制其他依赖金属离子的蛋白酶,例如依赖钙的半胱氨酸蛋白酶。作为抗凝血剂时,通常使用 EDTA 的二钠或三钾盐。最佳浓度为每 mL 血液 1.5mg。
用于消除痕量重金属对酶的抑制作用,并抑制需要二价阳离子作为辅助因子的酶。

Preparation Note

室温下溶于水的最大浓度可达 1.45M。该溶液的 pH 值约为 10 至 11,而且粘度较大。

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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