E4660
泽兰黄素
≥97% (HPLC)
别名:
3′,5-Dihydroxy-4′,6,7-trimethoxyflavone, 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one, 6-Methoxyluteolin 4′,7-dimethyl ether, NSC 106402
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所有图片(1)
About This Item
经验公式（希尔记法）:
C18H16O7
CAS号:
分子量:
344.32
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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质量水平
方案
≥97% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: >10 mg/mL
储存温度
room temp
SMILES字符串
COc1ccc(cc1O)C2=CC(=O)c3c(O)c(OC)c(OC)cc3O2
InChI
1S/C18H16O7/c1-22-12-5-4-9(6-10(12)19)13-7-11(20)16-14(25-13)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3
InChI key
KLAOKWJLUQKWIF-UHFFFAOYSA-N
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应用
Eupatorin has been used as reference standard for characterization of Artemisia extracts using mass spectrometry (MS).
生化/生理作用
Eupatorin acts as an antiproliferative in cells expressing the CYP1A- family. It induces G2/M block follow by apoptosis in cells expressing the CYP1A- family. It also functions as an anti-inflammatory.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Iva Dolečková et al.
Fitoterapia, 83(6), 1000-1007 (2012-06-16)
Flavone eupatorin is one of the constituents of Orthosiphon stamineus, a medicinal herb used in folk medicine in South East Asia for treatment of various disorders. In our study, we investigated the antiproliferative properties of a chloroform extract of the
Yit Hong Loon et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 816(1-2), 161-166 (2005-01-25)
A simple liquid chromatographic method was developed for the simultaneous determination of flavonoids from Orthosiphon stamineus Benth, namely sinensitin, eupatorin and 3'-hydroxy-5,6,7,4'-tetramethoxyflavone, in plasma. Prior to analysis, the flavonoids and the internal standard (naproxen) were extracted from plasma samples using
Mun Fei Yam et al.
Journal of acupuncture and meridian studies, 5(4), 176-182 (2012-08-18)
Orthosiphon stamineus extracts contain three flavonoids (3'-hydroxy-5,6,7,4'-tetramethoxyflavone, sinensetin, and eupatorin) as bioactive substances. Previous reported high performance liquid chromatography- ultraviolet (HPLC-UV) methods for the determination of these flavonoids have several disadvantages, including unsatisfactory separation times and not being well validated
Bioactive Phenolics of the Genus Artemisia (Asteraceae): HPLC-DAD-ESI-TQ-MS/MS Profile of the Siberian Species and Their Inhibitory Potential Against
Olennikov DN, et al.
Frontiers in Pharmacology, 9 (2018)
I M Lyckander et al.
Prostaglandins, leukotrienes, and essential fatty acids, 54(4), 239-246 (1996-04-01)
15-Lipoxygenase from soybeans is inactivated by bubbling air through enzyme solutions. This inactivation is prevented by flavonoids from the East Asian medicinal plant Orthosiphon spicatus, previously found to be inhibitors of the enzyme. 5,7,4'-Trimethylapigenin, eupatorin and 5,7,3',4'-tetramethylluteolin show the strongest
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