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Merck
CN

E4504

-8,11,14-二十碳三烯酸

≥99%

别名:

双-同-γ-亚麻酸, 顺式-8,11,14-二十烷三烯酸甲酯

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关于此项目

线性分子式:
CH3(CH2)3(CH2CH=CH)3(CH2)6CO2H
化学文摘社编号:
分子量:
306.48
UNSPSC Code:
12352211
NACRES:
NA.25
PubChem Substance ID:
EC Number:
217-233-0
Beilstein/REAXYS Number:
1796533
MDL number:
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产品名称

-8,11,14-二十碳三烯酸, ≥99%

InChI key

HOBAELRKJCKHQD-QNEBEIHSSA-N

InChI

1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-

SMILES string

CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O

biological source

plant oil (Borage)

assay

≥99%

form

viscous liquid

refractive index

n20/D 1.478 (lit.)

functional group

carboxylic acid

lipid type

omega FAs

shipped in

ambient

storage temp.

−20°C

Quality Level

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存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

143.6 °F - closed cup

flash_point_c

62 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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R M Hamilton et al.
Lipids, 16(5), 374-376 (1981-05-01)
Possible relationships between zinc and essential fatty acid metabolism have been assessed using plasma samples obtained from 39 cystic fibrosis patients. The fatty acid composition of plasma phospholipids was analyzed by capillary gas liquid chromatography and zinc levels were measured
C Thijs et al.
European journal of clinical nutrition, 54(3), 234-238 (2000-03-14)
To evaluate whether levels of n-6 long chain polyunsaturated fatty acids (LCPs) in human breast milk are related to the mother's atopic constitution, and whether a decreased level can be restored by gamma-linolenic acid supplementation. Cross-sectional study and dietary supplementation
Liping Du et al.
The Journal of pharmacology and experimental therapeutics, 316(1), 371-379 (2005-09-20)
The epidermis expresses cyclooxygenases, lipoxygenases, and cytochromes P450, which utilize arachidonic acid to generate a diverse array of lipid mediators affecting epidermal cellular differentiation and functions. Recent studies show that mouse epidermis expresses CYP2B19, a keratinocyte-specific epoxygenase that generates 11,12-
R D Abraham et al.
Atherosclerosis, 81(3), 199-208 (1990-04-01)
Low levels of essential polyunsaturated fatty acids of the n-6 series are associated with coronary heart disease. Linoleic acid, but not gamma-linolenic acid requires the activity of delta 6-desaturase for its conversion to dihomo-gamma-linolenic and arachidonic acid. Evening primrose oil
B C Melnik et al.
Journal of the American Academy of Dermatology, 21(3 Pt 1), 557-563 (1989-09-01)
Our hypothesis on the origin of atopy links alterations in omega-6-fatty acid metabolism in atopic persons (i.e., reduced formation of delta-6-desaturase products) to deficient T cell differentiation and function. We suggest that a relative deficiency in dihomo-gamma-linolenic acid-derived prostaglandin E1

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