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About This Item
经验公式（希尔记法）:
C51H64N12O12S2
CAS号:
分子量:
1101.26
Beilstein:
78671
MDL编号:
UNSPSC代码:
51101500
PubChem化学物质编号:
推荐产品
方案
90-95%
作用机制
DNA synthesis | interferes
储存温度
2-8°C
SMILES字符串
CS[C@H]1SC[C@@H]2N(C)C(=O)[C@H](C)NC(=O)[C@@H](COC(=O)[C@H](C(C)C)N(C)C(=O)[C@H]1N(C)C(=O)[C@H](C)NC(=O)[C@@H](COC(=O)[C@H](C(C)C)N(C)C2=O)NC(=O)c3cnc4ccccc4n3)NC(=O)c5cnc6ccccc6n5
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一般描述
Chemical structure: peptide
生化/生理作用
Powerful antimicrobial and antitumor agent; selectively inhibits nucleic acid synthesis in vitro. Binds to DNA by a bifunctional mode of intercalation.
其他说明
A cyclodepsipeptide antibiotic with quinoxaline functionality
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Repr. 2
储存分类代码
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
Echinomycin: a bifunctional intercalating antibiotic.
M J Waring et al.
Nature, 252(5485), 653-657 (1974-12-20)
K R Fox et al.
Nucleic acids research, 18(8), 1957-1963 (1990-04-25)
DNA fragments containing the sequence CG(AT)nCG have been used in footprinting experiments to assess the effect of echinomycin, which binds to CG steps, on the structure of the central AT region. DNAase I normally cuts ApT much better than TpA;
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