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形式
solid
质量水平
颜色
white
溶解性
H2O: soluble
alcohol: soluble
储存温度
2-8°C
SMILES字符串
O[C@H]([C@@H](O)C(O)=O)C(O)=O.CNC[C@H](O)c1ccc(O)c(O)c1
InChI
1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
InChI key
YLXIPWWIOISBDD-NDAAPVSOSA-N
基因信息
human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)
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一般描述
Epinephrine is a hormone, which is also termed as adrenaline. It is a monoamine and catecholamine.
应用
(-)Epinephrine (+)-bitartrate salt has been used:
- to test the possible existence of β-adrenergic vasodilation
- to infuse into the adipose region to minimize blood loss and tissue contamination
- as a platelet agonist in the preparation of optimal platelet aggregometry 96-well plates
- in the measurement of total superoxide dismutase (tSOD) enzymatic activity
生化/生理作用
Epinephrine is mainly liberated from adrenal medulla in response to stress, that is facilitated through sympathetic fibers.
肾上腺素能受体激动剂。
特点和优势
This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors, β-Adrenoceptors and Dopamine, Norepinephrine and Epinephrine Synthesis pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
注意
Light sensitive
警示用语:
Danger
危险声明
危险分类
Acute Tox. 1 Oral
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
监管及禁止进口产品
Chapter 4 - Substances Involved in Neurotransmission
Nutritional and Herbal Therapies for Children and Adolescents (2010)
Aerobic exercise training lowers platelet reactivity and improves platelet sensitivity to prostacyclin in pre-and postmenopausal women
Journal of Thrombosis and Haemostasis, 15(12), 2419-2431 (2017)
Comp Biochem Physiol A Mol Integr Physiol
The Journal of Experimental Biology, 202(8), 1005-1013 (1999)
CXCL5 secreted from adipose tissue-derived stem cells promotes cancer cell proliferation
Oncology Letters, 15(2), 1403-1410 (2018)
Human molecular genetics, 20(8), 1467-1477 (2011-01-25)
The gene coding for centrosomal protein 290 (CEP290), a large multidomain protein, is the most frequently mutated gene underlying the non-syndromic blinding disorder Leber's congenital amaurosis (LCA). CEP290 has also been implicated in several cilia-related syndromic disorders including Meckel-Gruber syndrome
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