E4267
9-乙基鸟嘌呤
别名:
2-氨基-9-乙基-6-羟基嘌呤, 6-氨基-9-乙基-2-羟基嘌呤
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关于此项目
经验公式（希尔记法）:
C7H9N5O
化学文摘社编号:
分子量:
179.18
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Assay:
≥98%
Form:
powder
Solubility:
1 M NaOH: 9.80-10.20 mg/mL, clear, colorless to faintly yellow
Storage temp.:
2-8°C
InChI key
WDOYBEPLTCFIRQ-UHFFFAOYSA-N
SMILES string
CCn1cnc2C(=O)N=C(N)Nc12
InChI
1S/C7H9N5O/c1-2-12-3-9-4-5(12)10-7(8)11-6(4)13/h3H,2H2,1H3,(H3,8,10,11,13)
assay
≥98%
form
powder
solubility
1 M NaOH: 9.80-10.20 mg/mL, clear, colorless to faintly yellow
storage temp.
2-8°C
Quality Level
Application
9-Ethylguanine (9-EtG) is used as a DNA model base for a variety of physical chemical studies of organometallic complexes.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Seiji Komeda et al.
Journal of the American Chemical Society, 124(17), 4738-4746 (2002-04-25)
The reactions of the dinuclear platinum(II) complexes, [[cis-Pt(NH(3))(2)](2)(mu-OH)(mu-pz)](NO(3))(2) (1, pz = pyrazolate), [[cis-Pt(NH(3))(2)](2)(mu-OH)(mu-1,2,3-ta-N1,N2)](NO(3))(2) (2, 1,2,3-ta = 1,2,3-triazolate), and a newly prepared [[cis-Pt(NH(3))(2)](2)(mu-OH)(mu-4-phe-1,2,3-ta-N1,N2)](NO(3))(2) (3, 4-phe-1,2,3-ta = 4-phenyl-1,2,3-triazolate), whose crystal structure was determined, with 9-ethylguanine (9EtG) have been monitored in aqueous solution
Sudeshna Roy et al.
Journal of inorganic biochemistry, 103(9), 1278-1287 (2009-08-07)
Two chelating ligands based on secondary amines have been selected to prepare four new Pt(II) compounds. The ligands bis(pyridine-2-yl)amine, abbreviated dpa, and bis(pyrimidine-2-yl)amine, abbreviated dipm, are chosen to design a rigid chelating motif to allow the study of subtle differences
A highly flexible dinuclear ruthenium(II)-platinum(II) complex: crystal structure and binding to 9-ethylguanine.
Karlijn van der Schilden et al.
Angewandte Chemie (International ed. in English), 43(42), 5668-5670 (2004-10-21)
Sudeshna Roy et al.
Dalton transactions (Cambridge, England : 2003), 48(48), 10846-10860 (2009-12-22)
The reaction of the redox-active ligand, Hpyramol (4-methyl-2-N-(2-pyridylmethyl)aminophenol) with K(2)PtCl(4) yields monofunctional square-planar [Pt(pyrimol)Cl], PtL-Cl, which was structurally characterised by single-crystal X-ray diffraction and NMR spectroscopy. This compound unexpectedly cleaves supercoiled double-stranded DNA stoichiometrically and oxidatively, in a non-specific manner
Eva Corral et al.
Inorganic chemistry, 46(16), 6715-6722 (2007-07-10)
The binding capability of three ruthenium polypyridyl compounds of structural formula [Ru(apy)(tpy)Ln-](ClO4)(2-n) [1a-c; apy = 2,2'-azobis(pyridine), tpy = 2,2':6',2''-terpyridine, L = Cl, H2O, CH3CN] to a fragment of DNA was studied. The interaction between each of these complexes and the
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