跳转至内容
Merck
CN
所有图片(1)

主要文件

查看所有文档

E3763

Sigma-Aldrich

乙氧基试卤灵

≥98% (TLC), powder

别名:

7-乙氧基-3H-吩恶嗪-3-酮, O 7 -乙基试卤灵, 乙氧基试卤灵

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C14H11NO3
CAS号:
5725-91-7
分子量:
241.24
Beilstein:
225973
MDL编号:
MFCD00037661
UNSPSC代码:
12161501
PubChem化学物质编号:
24894527
NACRES:
NA.47

质量水平

200

方案

≥98% (TLC)

表单

powder

储存条件

(Tightly closed. Dry)

技术

activity assay: suitable

颜色

orange to red

mp

223-225 °C (lit.)

溶解性

chloroform: 9.80-10.20 mg/mL, clear, orange

适用性

suitable for fluorescence

储存温度

−20°C

SMILES字符串

CCOc1ccc2N=C3C=CC(=O)C=C3Oc2c1.Fc4c(F)c(F)c(OC(=O)CNC(=O)OCC5c6ccccc6-c7ccccc57)c(F)c4F

InChI

1S/C23H14F5NO4.C14H11NO3/c24-17-18(25)20(27)22(21(28)19(17)26)33-16(30)9-29-23(31)32-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15;1-2-17-10-4-6-12-14(8-10)18-13-7-9(16)3-5-11(13)15-12/h1-8,15H,9-10H2,(H,29,31);3-8H,2H2,1H3

InChI key

ZOSYTBPPLWBBKM-UHFFFAOYSA-N

正在寻找类似产品? 访问 产品对比指南

一般描述

试卤灵被用作不同细胞色素 P (CYP) 亚型的标记物或底物。试卤灵乙醚是 3-甲基胆蒽处理动物的微粒体代谢的首选试卤灵乙醚。
试卤灵（Resorufin）是刃天青的还原产物，也称为阿尔玛蓝（Alamar Blu）。它在较长的波长下发射荧光，并且其羟基可进行灵活的修饰。

适用研究领域：细胞信号传导

应用

试卤灵乙醚适用于研究细胞色素 P450 同工酶 1A1 和 1A2 的脱烷基活性，其中芳基烷基和烷基异硫氰酸盐及其谷胱甘肽、半胱氨酸和 A′-乙酰半胱氨酸结合物用作抑制剂。适合于研究细胞色素 P450 活性 (CYP1A1) 的乙氧基试卤灵-O-脱乙基酶 (EROD) 活性。

底物

细胞色素 P450 连接酶 CXPIA1/2 的荧光底物

底物

产品编号
说明
价格

M1544

Resorufin methyl ether

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000371458
0000317525
0000371458
0000317525
0000185655

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

V Villa-Cruz et al.
Chemosphere, 74(9), 1145-1151 (2009-01-16)
Tilapia fish (Oreochromis niloticus) were fed with enriched diets containing broccoli and its phytochemical sulforaphane over 30 d. The levels of cytochrome P450, superoxide dismutase, catalase, lipid peroxidation and glutathione-S-transferase activities were measured. Basal value of cytochrome P450 activity was
Reduction of resazurin to resorufin catalyzed by gold nanoparticles: dramatic reaction acceleration by laser or LED plasmon excitation
Alejo CJ, et al.
Catalysis Science & Technology, 1(8), 1506-1511 (2011)
C C Conaway et al.
Carcinogenesis, 17(11), 2423-2427 (1996-11-01)
A series of arylalkyl and alkyl isothiocyanates, and their glutathione, cysteine, and N-acetylcysteine conjugates were used to study their inhibitory activity toward the dealkylation of ethoxyresorufin (EROD), pentoxyresorufin (PROD), and methoxyresorufin (MROD) in liver microsomes obtained from the 3-methylcholanthrene or
A resorufin derivative as a fluorogenic indicator for cell viability
Ishiyama M, et al.
Analytical Sciences, 15(10), 1025-1028 (1999)
Jong Hwan Sung et al.
Biotechnology and bioengineering, 104(3), 516-525 (2009-07-04)
We describe an in situ fluorescence optical detection system to demonstrate real-time and non-invasive detection of reaction products in a microfluidic device while under perfusion within a standard incubator. The detection system is designed to be compact and robust for
查看所有相关文献

商品

一期药物代谢

一期生物转化反应在药物上引入或暴露官能团，目的是增加化合物的极性。尽管一期药物代谢发生在大多数组织中，但代谢的主要和首过部位发生在肝循环期间。

Phase I Drug Metabolism

Phase I biotransformation reactions increase drug compound polarity, mainly occurring in hepatic circulation.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门