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Merck
CN

E1904

Sigma-Aldrich

Ethyl-3,4-dephostatin

>99% (HPLC), solid

别名:

3,4-Dihydroxy-N-ethyl-N-nitrosoaniline

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About This Item

经验公式(希尔记法):
C8H10N2O3
分子量:
182.18
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

>99% (HPLC)

形式

solid

颜色

brown

溶解性

DMSO: soluble 22 mg/mL
H2O: soluble 8 mg/mL

储存温度

2-8°C

SMILES字符串

CCN(N=O)c1ccc(O)c(O)c1

InChI

1S/C8H10N2O3/c1-2-10(9-13)6-3-4-7(11)8(12)5-6/h3-5,11-12H,2H2,1H3

InChI key

ZTXUSFPBLYQDDN-UHFFFAOYSA-N

生化/生理作用

Stable analog of dephostatin. Selective inhibitor of protein tyrosine phosphatase 1B and SHPTP-1. Does not inhibit CD45-associated phosphatases.

特点和优势

This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

注意

Store under nitrogen

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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J H Kim et al.
Cell death & disease, 4, e588-e588 (2013-04-13)
Hypoxia enhances the proliferation and migration of adipose-derived stem cells (ASCs) via the generation of reactive oxygen species (ROS). Therefore, this study primarily investigated whether or not ROS generation could regulate microRNA-210 (miR-210) expression, and increase proliferation/migration of ASCs. In

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