推荐产品
方案
≥99.45% (HPLC)
质量水平
表单
powder
mp
88-90 °C (lit.)
溶解性
95% ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
荧光
λex 323 nm; λem 386 nm
SMILES字符串
CCOc1ccc2C=CC(=O)Oc2c1
InChI
1S/C11H10O3/c1-2-13-9-5-3-8-4-6-11(12)14-10(8)7-9/h3-7H,2H2,1H3
InChI key
LIFAQMGORKPVDH-UHFFFAOYSA-N
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应用
7-乙氧基香豆素已被用于研究重组P450的功能活性。) 它还被用作 体外S-华法林7-羟基化作用和高效液相色谱(HPLC)分析的内标物。
生化/生理作用
7-乙氧基香豆素是细胞色素P450 的一种底物。
CYP2B6 的底物
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Unravelling the molecular determinants of bee sensitivity to neonicotinoid insecticides
Current Biology, 28(7), 1137-1143 (2018)
Functional characterization of human CYP2C9 allelic variants in COS-7 cells
Frontiers in Pharmacology, 7, 98-98 (2016)
Biotechnology and bioengineering, 105(1), 184-194 (2009-09-01)
Early detection of kinetic, metabolic, and toxicity (ADME-Tox) profiles for new drug candidates is of crucial importance during drug development. This article describes a novel in vitro system for the incubation of precision-cut liver slices (PCLS) under flow conditions, based
Drug metabolism and disposition: the biological fate of chemicals, 36(11), 2166-2170 (2008-08-02)
Recently, wild-type and mutant forms of bacterial cytochrome P450 BM3 (CYP102A1) have been found to metabolize various drugs through reactions similar to those catalyzed by human cytochromes P450 (P450s). Therefore, it has been suggested that CYP102A1 may be used to
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 149(3), 334-339 (2008-09-23)
To evaluate the feasibility of using the silkworm as a model animal for screening drug candidates, we examined whether the lethal dose of cytotoxic chemicals in silkworm, Bombyx mori, were consistent with those in mammals, and compared the metabolic pathways
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