生物来源
mouse submaxillary glands
质量水平
产品线
BioReagent
检测方案
≥98% (SDS-PAGE)
形式
lyophilized powder
效能
0.02-2.0 ng/mL EC50
包装
pkg of 0.1 mg
储存条件
avoid repeated freeze/thaw cycles
技术
cell culture | mammalian: suitable
杂质
endotoxin, tested
颜色
white
UniProt登记号
储存温度
2-8°C
基因信息
mouse ... Egf(13645)
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相关类别
一般描述
Epidermal growth factor (EGF) is the member of EGF-like family of growth factors, that binds to EGF receptor. It is majorly expressed in kidney, parotid gland and salivary gland.
应用
Epidermal Growth Factor from murine submaxillary gland has been used
- in studying its effects on the development of caustic esophageal stricture in rats
- for preparation of MCF-10A cell line
- for the culture of primary hair follicle stem cells from arbas cashmere goat (gHFSCs) and adhesion of hair follicles (HF)
生化/生理作用
Epidermal growth factor (EGF) blocks gastric acid and pepsin secretion and increases gastrointestinal cell proliferation. EGF stimulates proliferation and migration in bone marrow stromal cells (BMSC), that gives rise to osteoblasts, chondrocytes and adipocytes. It functions as a strong mitogenic factor for various cultured cells. Mutations in this gene is linked to hypomagnesemia. EGF plays a major role in the maintenance of hair and skin development.
外形
Lyophilized from 0.2 μm filtered solution in ammonium acetate buffer.
制备说明
Purified by gel filtration and ion-exchange chromatography.
分析说明
The biological activity is measured in a proliferation assay using BALB/MK cells.
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
动植物源性产品
Epidermal growth factor promotes proliferation of dermal papilla cells via Notch signaling pathway
Zhang H, et al.
Biochimie, 127(21), 10-18 (2016)
Effects of caffeic acid phenethyl ester and epidermal growth factor on the development of caustic esophageal stricture in rats
Koltuksuz U, et al.
Journal of Pediatric Surgery, 36(10), 1504-1509 (2001)
Expression of epidermal growth factor in human tissues
Kajikawa K, et al.
Virchows Archiv. A, Pathological Anatomy and Histopathology, 418(1), 27-32 (1991)
Subcellular localization of epidermal growth factor receptor in human submandibular gland
Lantini MS, et al.
Journal of Anatomy, 208(5), 595-599 (2006)
High-sensitivity TFA-free LC-MS for profiling histones
You J, et al.
Proteomics, 11(16), 3326-3334 (2011)
商品
Frequently asked questions about neural stem cells including NSC derivation, expansion and differentiation.
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