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生物来源
mouse
质量水平
重组
expressed in NSO cells
方案
>90% (SDS-PAGE)
表单
lyophilized powder
分子量
monomer calculated mol wt 49.6 kDa
60-65 kDa by SDS-PAGE (reducing)
包装
pkg of 200 μg
储存条件
avoid repeated freeze/thaw cycles
杂质
endotoxin, tested
UniProt登记号
储存温度
−20°C
基因信息
mouse ... Efnb2(13642)
生化/生理作用
Member of ephrin ligand family that binds Eph receptor tyrosine kinases (EphA4, EphB1, EphB2, EphB3, and EphB4). Involved in pattern formation and morphogenesis. Ephrin-B2 can be detected on monocytes, mesangial cells, CD34+ stem cells, bone marrow fibroblasts, activated melanocytes and melanoma cells, and pre-artery endothelial cells.
其他说明
Extracellular domain of mouse ephrin-B2 (amino acids 1-227) fused to the C-terminal 6X histidine-tagged Fc region of human IgG1.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.
分析说明
The biological activity is measured by its ability to bind immobilized recombinant mouse EphB2/Fc in ELISA.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
Tiancheng Li et al.
Journal of cellular physiology, 236(3), 2070-2086 (2020-08-03)
Intermittent parathyroid hormone (PTH) promotes periodontal repair, but the underlying mechanisms remained unclear. Recent studies found that ephrinB2-EPHB4 forward signaling mediated the anabolic effect of PTH in bone homeostasis. Considering the similarities between cementum and bone, we aimed to examine
Takahiro Sawada et al.
PloS one, 12(7), e0180785-e0180785 (2017-07-08)
We previously reported that EphA4, a member of the Eph family of receptor tyrosine kinases, is an important modulator of growth hormone (GH) signaling, leading to augmented synthesis of insulin-like growth factor 1 (IGF1) for postnatal body growth. In the
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