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Merck
CN

E0276

EPPS

BioPerformance Certified, suitable for cell culture, ≥99.5% (titration)

别名:

4-(2-羟乙基)-1-哌嗪丙磺酸, 4-羟乙基哌嗪丙磺酸, N-(2-羟乙基)哌嗪-N′-(3-丙磺酸), HEPPS

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关于此项目

经验公式(希尔记法):
C9H20N2O4S
化学文摘社编号:
分子量:
252.33
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
EC Number:
240-198-8
Beilstein/REAXYS Number:
3957385
MDL number:
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产品名称

EPPS, BioPerformance Certified, suitable for cell culture, ≥99.5% (titration)

InChI key

OWXMKDGYPWMGEB-UHFFFAOYSA-N

InChI

1S/C9H20N2O4S/c12-8-7-11-5-3-10(4-6-11)2-1-9-16(13,14)15/h12H,1-9H2,(H,13,14,15)

SMILES string

OCCN1CCN(CCCS(O)(=O)=O)CC1

grade

BioPerformance Certified

assay

≥99.5% (titration)

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin and Total Aerobic Microbial Count, tested

pH

7.3-8.7

useful pH range

7.3-8.7

pKa (25 °C)

8.0

pKa 

8

mp

237-239 °C (lit.)

solubility

H2O: 25 g + 50 mL, clear, colorless

cation traces

heavy metals (as Pb): ≤5 ppm

λmax

A290 at ≤0.1 (C=33% w/w)

application(s)

diagnostic assay manufacturing

Quality Level

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Application

EPPS may be used as a buffer solution to stabilize the pH in sea water samples during the titration experiments.

Features and Benefits

  • BioPerformance Certified, high-quality level (400), ensures reliable and consistent results.
  • Suitable for mammalian cell culture techniques

General description

EPPS or 4-(2-hydroxyethyl)piperazine-1-propanesulfonic acid (HEPPS) is a zwitterionic buffer substance from the group of good buffers. It effectively maintains constant pH in a solution, which is necessary for many biological and biochemical reactions. EPPS buffer is widely used in cell culture experiments and biological research.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The characteristics of Fe speciation and Fe-binding ligands in the Mariana back-arc hydrothermal plumes
Wang H R, et al.
Geochimica et Cosmochimica Acta, 292, 24-36 (2021)
Equilibrium studies, synthesis, and characterization of zwitterionic buffer (HEPES and HEPPS) dimethyltin (IV) complexes
Mahmoud M, et al.
Main Group Chemistry, 6(2) (2007)
lonization Enthalpies of Some Common Zvvitterionic Hydrogen-lon Buffers (HEPES, PIPES, HEPPS and BES) for Biological Research
Roig T, et al.
Journal of Separation Science, 993(47), 899-90j-899-90j (1993)
Feng Xie et al.
Cancer letters, 364(2), 106-117 (2015-05-17)
Cervical cancer is often associated with eosinophil (EOS) infiltration, but the source and the role of EOS are still largely unknown. Our previous work has established that thymic stromal lymphopoietin (TSLP) can stimulate the growth of cervical cancer cell in
Xiannu Jin et al.
Journal of pharmacological and toxicological methods, 70(2), 188-194 (2014-08-26)
Malaria is a major health concern and affects over 300million people a year. Accordingly, there is an urgent need for new efficacious anti-malarial drugs. A major challenge in developing new anti-malarial drugs is to design active molecules that have preferable

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