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质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to off-white
溶解性
H2O: >30 mg/mL
创始人
Sanofi Aventis
储存温度
2-8°C
SMILES字符串
O.CS(O)(=O)=O.O=C1CN2[C@@H]3C[C@H](C[C@H]2CC1C3)OC(=O)c4c[nH]c5ccccc45
InChI
1S/C19H20N2O3.CH4O3S.H2O/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17;1-5(2,3)4;/h1-4,9,11-14,20H,5-8,10H2;1H3,(H,2,3,4);1H2/t11?,12-,13+,14+;;
InChI key
QTFFGPOXNNGTGZ-BHSFMSKKSA-N
生化/生理作用
Dolasetron mesylate hydrate is a highly selective serotonin 5-HT3 receptor antagonist.
Dolasetron mesylate hydrate is a highly specific and selective serotonin 5-HT3 receptor antagonist, not shown to have activity at other known serotonin receptors and with low affinity for dopamine receptors.
特点和优势
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Edward B Silberstein
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 49(4), 546-549 (2008-03-18)
The goal of this study was to reduce the salivary symptoms of pain and xerostomia caused by 131I therapy for papillary and follicular thyroid carcinoma. In a single-blind controlled prospective study of 60 patients, we investigated whether pilocarpine, 5 mg
Mehdi Hamadani et al.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 13(2), 69-75 (2007-09-18)
The last decade has witnessed the great impact of 5-hydroxytryptamine-3 receptor (5-HT(3))antagonists in revolutionizing the management of platinum-based chemotherapy-induced acute nausea and vomiting (CINV). However, despite the availability of a variety of 5-HT(3) antagonists, little data is published to support
Lauren Trepanier
Journal of feline medicine and surgery, 12(3), 225-230 (2010-03-03)
The control of nausea and vomiting in cats is important in order to prevent the development of food aversion, anorexia (with its associated complications of weight loss and dehydration), and hepatic lipidosis. There are several antiemetic drugs that are clinically
[Pharmacokinetic and pharmacodynamic features of palonosetron].
Armando A Genazzani et al.
Tumori, 94(2), suppl 6-suppl13 (2008-06-21)
Sarah Turner et al.
Journal of clinical anesthesia, 19(8), 622-625 (2007-12-18)
A 52-year-old woman with hypertension and Graves' disease was scheduled for surgical removal of a meningioma. Intraoperative events were significant for hypotension requiring a vasopressin infusion. Prophylactic dolasetron was administered to the patient before emergence. The patient's trachea was easily
商品
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