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Merck
CN

D9286

Sigma-Aldrich

乙基对硫磷

≥90%, oil

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别名:
O,O-二乙基磷酸对硝基苯酯, 对氧磷, 对硝基苯磷酸二乙酯
线性分子式:
O2NC6H4OP(O)(OC2H5)2
CAS号:
分子量:
275.20
Beilstein:
1915526
EC 号:
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77

质量水平

检测方案

≥90%

形式

oil

颜色

yellow

折射率

n20/D 1.51 (lit.)

密度

1.274 g/mL at 25 °C (lit.)

储存温度

2-8°C

SMILES字符串

CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3

InChI key

WYMSBXTXOHUIGT-UHFFFAOYSA-N

基因信息

human ... PON1(5444)

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应用

乙基对氧磷被用作对氧磷酶(PON)活性测定的底物。 它还被用作脂肪酶抑制剂,以研究安塞曲匹对体内高密度脂蛋白L3(HDL3)向HDL2的同型转移的影响。

生化/生理作用

强效不可逆乙酰胆碱酯酶抑制剂

注意

对空气敏感:在氩气下处理

外形

油性液体

象形图

Skull and crossbonesEnvironment

警示用语:

Danger

危险声明

危险分类

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品
剧毒化学品

分析证书(COA)

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Elena Grao-Cruces et al.
Biomedicines, 9(11) (2021-11-28)
High-density lipoproteins (HDLs) play an important role in reverse cholesterol transport and present antioxidant properties, among others. In the central nervous system (CNS), there are HDLs, where these lipoproteins could influence brain health. Owing to the new evidence of HDL
Inhibition of cholesteryl ester transfer protein increases cholesteryl ester content of large HDL independently of HDL-to-HDL homotypic transfer: in vitro vs in vivo comparison using anacetrapib and dalcetrapib
Johns DG, et al.
European Journal of Pharmacology, 762, 256-262 (2015)
Altered lipoproteins in patients with systemic lupus erythematosus are associated with augmented oxidative stress: a potential role in atherosclerosis
Park JK, et al.
Arthritis Research & Therapy, 18(1), 306-306 (2016)
Association between ethnicity and obesity with high-density lipoprotein (HDL) function and subclass distribution
Woudberg NJ, et al.
Lipids in Health and Disease, 15(1), 92-92 (2016)
Exercise intervention alters HDL subclass distribution and function in obese women
Woudberg NJ, et al.
Lipids in Health and Disease, 17(1), 232-232 (2018)

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