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Merck
CN

D9050

Sigma-Aldrich

N-乙酰基-2,3-脱氢-2-脱氧神经氨酸

≥93% (TLC)

别名:

2,3-脱氢-2-脱氧-N-乙酰神经氨酸

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About This Item

经验公式(希尔记法):
C11H17NO8
CAS号:
分子量:
291.25
Beilstein:
8722455
EC 号:
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25

生物来源

synthetic (organic)

质量水平

方案

≥93% (TLC)

表单

powder

旋光性

[α]20/D 40.8 to 51.0 °, c = 0.66% (w/v) in water

颜色

white

溶解性

H2O: soluble 50 mg/mL, clear, colorless

储存温度

−20°C

SMILES字符串

CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O

InChI

1S/C11H17NO8/c1-4(14)12-8-5(15)2-7(11(18)19)20-10(8)9(17)6(16)3-13/h2,5-6,8-10,13,15-17H,3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,8+,9+,10+/m0/s1

InChI key

JINJZWSZQKHCIP-UFGQHTETSA-N

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应用

N-乙酰基-2,3-脱氢-2-脱氧神经氨酸(NADNA),一种特异性内源性神经氨酸酶(NEU)抑制剂,可用于研究内源性神经氨酸酶在发育中的作用,在神经过程和通路中的功能,以及其他依赖唾液酸化-脱唾液酸化循环的过程。

生化/生理作用

细菌、病毒和动物神经氨酸酶(唾液酸酶)的抑制剂。

其他说明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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分析证书(COA)

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Bioorganic & medicinal chemistry, 17(13), 4595-4603 (2009-05-20)
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Antimicrobial agents and chemotherapy, 52(10), 3484-3491 (2008-08-13)
Oseltamivir (Tamiflu) and zanamivir (Relenza), two extensively used clinically effective anti-influenza drugs, are viral sialidase (also known as neuraminidase) inhibitors that prevent the release of progeny virions and thereby limit the spread of infection. Recently mortalities and neuropsychiatric events have
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Glycobiology, 17(1), 68-81 (2006-09-16)
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