所有图片(1)
About This Item
经验公式（希尔记法）:
C13H12N7OCl3 · HCl
CAS号:
分子量:
425.10
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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质量水平
方案
>98% (HPLC)
表单
solid
颜色
yellow
溶解性
DMSO: soluble 30 mg/mL
H2O: insoluble
储存温度
2-8°C
SMILES字符串
NC1=NC(N)=C(Cl)N=C1C(NC(NCC2=CC(Cl)=C(Cl)C=C2)=N)=O.Cl
InChI
1S/C13H12Cl3N7O.ClH/c14-6-2-1-5(3-7(6)15)4-20-13(19)23-12(24)8-10(17)22-11(18)9(16)21-8;/h1-3H,4H2,(H4,17,18,22)(H3,19,20,23,24);1H
InChI key
LPHAOBPPRPXQLQ-UHFFFAOYSA-N
生化/生理作用
Inhibits Na+/Ca2+ exchanger, Na+ transport and sarcoplasmic reticulum Ca2+ release channels.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Shaminder Kaur et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 129(4), 435-443 (2009-04-02)
The present study was designed to investigate the possible neuroprotective effect of digoxin induced pharmacological preconditioning (PP) and its probable mechanism. Bilateral carotid artery occlusion (BCAO) of 17 min followed by reperfusion for 24 h was employed to produce ischemia
Friedrich Brunner et al.
Cardiovascular research, 60(2), 355-364 (2003-11-14)
The oxidant species peroxynitrite, the reaction product of nitric oxide (NO.) and superoxide, has been implicated in several pathophysiological conditions of the heart. Here, we studied the mechanism of peroxynitrite-induced cardiac depression using specific drugs and simultaneous analyses of myocardial
Manu Hegde et al.
The Journal of pharmacology and experimental therapeutics, 310(1), 67-74 (2004-03-11)
Previously, we demonstrated that malignant glioma cell lines have increased intracellular pH (pHi) as a result of increased activities of the type I sodium/hydrogen exchanger (NHE1). This alkalotic pHi of 7.2 to 7.4 is favorable for augmented glycolysis, DNA synthesis
C Soto et al.
The Journal of experimental zoology, 289(1), 23-32 (2001-02-13)
The aim of this study was to analyze the relationship of the Na+/Ca2+ exchanger, cytosolic calcium, and chloride to the transepithelial transport of sodium in isolated frog skin. Sodium transport was measured as amiloride-inhibitable short circuit current (SCC). We studied
A S Arbab et al.
Nuclear medicine communications, 24(2), 155-166 (2003-01-28)
Our aim was to determine whether the Ca2+ ion or cell membrane Ca2+ and Na+/Ca2+ ion transport systems are involved in maintaining the cell-associated activity of technetium-99m-hexakis-methoxy-isobutyl-isonitrile (99mTc-MIBI) and technetium-99m-ethylene-bis[bis(2-ethoxyethyl)phosphin] (99mTc-tetrofosmin) in tumour cell lines. The cell-associated activities of 99mTc-MIBI
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