推荐产品
产品名称
1,2-二-O-月桂基-rac-甘油-3-戊二酸-6′-甲基雷洛芬酯, lipase substrate
质量水平
表单
solid
储存温度
2-8°C
SMILES字符串
CCCCCCCCCCCCOCC(COC(=O)CCCC(=O)Oc1ccc2N=C3C=CC(=O)C=C3Oc2c1C)OCCCCCCCCCCCC
InChI
1S/C45H69NO8/c1-4-6-8-10-12-14-16-18-20-22-31-50-34-38(51-32-23-21-19-17-15-13-11-9-7-5-2)35-52-43(48)25-24-26-44(49)53-41-30-29-40-45(36(41)3)54-42-33-37(47)27-28-39(42)46-40/h27-30,33,38H,4-26,31-32,34-35H2,1-3H3
InChI key
JEGLJLCZRAWOBI-UHFFFAOYSA-N
应用
用于脂肪酶的显色底物
生化/生理作用
1,2-二-O-月桂基-rac-甘油-3-戊二酸-6′-甲基雷洛芬酯(DGGR)具有更强的胰腺特异性。因此DGGR脂肪酶最好是作为spec cPL的替代品，用于疑似胰腺炎诊断病例中。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Validation of a commercial 1, 2-o-dilauryl-rac-glycero glutaric acid-(6?-methylresorufin) ester lipase assay for diagnosis of canine pancreatitis
Goodband E L, et al.
Veterinary record open, 5(1), e000270-e000270 (2018)
Breanne M Coady et al.
Journal of peptide science : an official publication of the European Peptide Society, 24(11), e3123-e3123 (2018-10-06)
Human hepatic lipase (hHL) is a cell surface associated enzyme that hydrolyzes triacylglycerols and phospholipids within circulating lipoproteins. We hypothesized that an amino acid sequence mimicking the major heparin binding domain (HBD) of hHL will displace hHL from cell surfaces.
Narmadaa Thyagarajan et al.
Lipids, 52(3), 189-205 (2017-02-17)
Macrophage lipoprotein lipase (LPL) induces lipid accumulation and promotes atherosclerosis. However, the effects of lipoprotein hydrolysis products generated by LPL on macrophage-derived foam cell formation are not clearly understood. Thus, we analyzed the transcriptomic response to hydrolysis products via microarray
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