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Merck
CN

D7400

2′-脱氧腺苷 一水合物

≥99%, synthetic (organic), powder

别名:

9-(2-脱氧-β- D -呋喃核糖基)腺嘌呤, 腺嘌呤脱氧核苷

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关于此项目

经验公式(希尔记法):
C10H13N5O3 · H2O
化学文摘社编号:
分子量:
269.26
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
213-488-7
MDL number:
Beilstein/REAXYS Number:
91015
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
Storage temp.:
2-8°C
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产品名称

2′-脱氧腺苷 一水合物, ≥99%

biological source

synthetic (organic)

Quality Segment

assay

≥99%

form

powder

solubility

water: 25 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

[H]O[H].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3

InChI

1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1

InChI key

OLXZPDWKRNYJJZ-RRKCRQDMSA-N

Application

2′-脱氧腺苷一水合物用于:
  • 作为核苷补充品成分
  • 作为标准品,估算增殖油棕胚性悬浮液中的DNA总甲基化率
  • 逆转无菌α基序(SAM)和含组氨酸-天冬氨酸(HD)结构域的蛋白(SAMHD1)
  • 抑制人类免疫缺陷病毒(HIV-1)和乙型肝炎病毒(HBV)

Biochem/physiol Actions

2′-脱氧腺苷(2′-dAdo),是脱氧核糖核苷,在能量应激的情况下可能被某些细胞用作能源,影响 cAMP的水平。 2′-dAdo 用于腺苷类似物在各种生物过程中功能的比较研究。


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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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O Magnus et al.
International journal of fertility, 38(2), 123-128 (1993-03-01)
To find differences in effect on sperm motility of agents that increase intracellular cAMP: manganese ion, methyl-isobutyl-xanthine (MIX), 2-deoxyadenosine, glucose, and Mn-MIX and Mn-glucose. Nine men with asthenozoospermia vs. fertile donors. Sperm was washed in Hepes-buffered saline, motility tested by
M Nakamura et al.
The Journal of biological chemistry, 257(23), 13945-13950 (1982-12-10)
Regulation of glucose metabolism in glycolysis by round spermatids was studied. Assay of activities of 11 glycolytic enzymes in cell-free spermatid extracts showed that hexokinase, phosphofructokinase, and glyceraldehyde-3-phosphate dehydrogenase had the lowest activities. When the cells were incubated with glucose
Nucleoside supplementation modulates mitochondrial DNA copy number in the dguok-/- zebrafish
Munro B, et al.
Human Molecular Genetics, 28(5), 796-803 (2018)



全球贸易项目编号

货号GTIN
D7400-1G04061826738429
D7400-250MG04061833048030
D7400-500MG04061833588475
D7400-25G04061833588468
D7400-5G04061833588482