推荐产品
生物来源
synthetic (organic)
质量水平
方案
≥99%
表单
powder
溶解性
water: 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
储存温度
2-8°C
SMILES字符串
[H]O[H].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3
InChI
1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1
InChI key
OLXZPDWKRNYJJZ-RRKCRQDMSA-N
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应用
2′-脱氧腺苷一水合物用于:
- 作为核苷补充品成分
- 作为标准品,估算增殖油棕胚性悬浮液中的DNA总甲基化率
- 逆转无菌α基序(SAM)和含组氨酸-天冬氨酸(HD)结构域的蛋白(SAMHD1)
- 抑制人类免疫缺陷病毒(HIV-1)和乙型肝炎病毒(HBV)
生化/生理作用
2′-脱氧腺苷(2′-dAdo),是脱氧核糖核苷,在能量应激的情况下可能被某些细胞用作能源,影响 cAMP的水平。 2′-dAdo 用于腺苷类似物在各种生物过程中功能的比较研究。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
历史批次信息供参考:
分析证书(COA)
Scientific reports, 7(1), 4043-4043 (2017-06-24)
Deuterated water (
SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-kappaB Activation
Testing, 28(2), 434-448 (2019)
International journal of fertility, 38(2), 123-128 (1993-03-01)
To find differences in effect on sperm motility of agents that increase intracellular cAMP: manganese ion, methyl-isobutyl-xanthine (MIX), 2-deoxyadenosine, glucose, and Mn-MIX and Mn-glucose. Nine men with asthenozoospermia vs. fertile donors. Sperm was washed in Hepes-buffered saline, motility tested by
The international journal of biochemistry & cell biology, 37(4), 797-808 (2005-02-08)
In this paper, we report that cells undergoing metabolic stress conditions may use the ribose moiety of nucleosides as energy source to slow down cellular damage. In fact, the phosphorolytic cleavage of the N-glycosidic bond of nucleosides generates, without energy
Biology of reproduction, 77(6), 960-969 (2007-09-01)
Activation of rapid motility apparently is one of the first steps of sperm capacitation and can be studied in vitro. Previously we found that 2-chloro-2'-deoxyadenosine or the catecholamine isoproterenol activates mouse sperm motility in vitro via a pathway mediated by
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