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主要文件

安全信息

D6898

Sigma-Aldrich

脱氧核糖核酸 钠盐 来源于鲱鱼睾丸

Type XIV

别名:

DNA

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10 MG
¥5,091.26
25 MG
¥10,047.77

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10 MG
¥5,091.26
25 MG
¥10,047.77

About This Item

MDL编号:
UNSPSC代码:
41106305
eCl@ss:
32160414
NACRES:
NA.51

¥5,091.26


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类型

Type XIV

表单

solid

储存温度

2-8°C

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此商品
MAK181MAK013MAK084
detection method

colorimetric, fluorometric

detection method

fluorometric

detection method

colorimetric, fluorometric

detection method

fluorometric

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

application(s)

cosmetics
food and beverages

application(s)

-

application(s)

cosmetics
food and beverages

application(s)

-

relevant disease(s)

endocrinological disorders, diabetes

relevant disease(s)

endocrinological disorders, diabetes; cancer

relevant disease(s)

endocrinological disorders, diabetes

relevant disease(s)

endocrinological disorders, diabetes; cancer

一般描述

来自鲱鱼睾丸的脱氧核糖核酸钠盐,也称为HtDNA,是DNA结合剂研究的天然DNA来源。 HtDNA的检出限约为5.0ng,光散射强度(I(LS))的线性范围为0.05 ~ 2.5 mµg。[1]

应用

从鲱鱼睾丸中提取的脱氧核糖核酸钠盐被用于研究调节DNA结构和功能的DNA结合剂。鲱鱼睾丸DNA也用于溶液中DNA行为的物理化学研究。

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

动植物源性产品
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    Assaf Marcus et al.
    Immunity, 49(4), 754-763 (2018-10-18)
    Detection of cytosolic DNA by the enzyme cGAS triggers the production of cGAMP, a second messenger that binds and activates the adaptor protein STING, which leads to interferon (IFN) production. Here, we found that in vivo natural killer (NK) cell killing
    X Du et al.
    Talanta, 55(1), 93-98 (2008-10-31)
    The interaction of histone with nucleic acids was characterized by light-scattering measurement using a common spectrofluorometer. Thereby, a sensitive and convenient method for the determination of nucleic acids was established. At pH 4.5-6.5, the interaction of histone with nucleic acids
    Matteo Gentili et al.
    Cell reports, 26(9), 2377-2393 (2019-02-28)
    Cytosolic DNA activates cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) synthase (cGAS), an innate immune sensor pivotal in anti-microbial defense, senescence, auto-immunity, and cancer. cGAS is considered to be a sequence-independent DNA sensor with limited access to nuclear DNA because of compartmentalization. However
    Larisa I Labzin et al.
    The EMBO journal, 38(21), e101365-e101365 (2019-08-31)
    Inflammasomes are potent innate immune signalling complexes that couple cytokine release with pro-inflammatory cell death. However, pathogens have evolved strategies to evade this cell autonomous system. Here, we show how antibodies combine with innate sensors in primary human macrophages to
    Renée M Van der Sluis et al.
    PLoS pathogens, 16(2), e1008151-e1008151 (2020-02-29)
    HIV latency is the major barrier to a cure for people living with HIV (PLWH) on antiretroviral therapy (ART) because the virus persists in long-lived non-proliferating and proliferating latently infected CD4+ T cells. Latently infected CD4+ T cells do not

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