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一般描述
来自鲱鱼睾丸的脱氧核糖核酸钠盐,也称为HtDNA,是DNA结合剂研究的天然DNA来源。 HtDNA的检出限约为5.0ng,光散射强度(I(LS))的线性范围为0.05 ~ 2.5 mµg。
应用
从鲱鱼睾丸中提取的脱氧核糖核酸钠盐被用于研究调节DNA结构和功能的DNA结合剂。鲱鱼睾丸DNA也用于溶液中DNA行为的物理化学研究。
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
动植物源性产品
从最新的版本中选择一种:
分析证书(COA)
Immunity, 49(4), 754-763 (2018-10-18)
Detection of cytosolic DNA by the enzyme cGAS triggers the production of cGAMP, a second messenger that binds and activates the adaptor protein STING, which leads to interferon (IFN) production. Here, we found that in vivo natural killer (NK) cell killing
Talanta, 55(1), 93-98 (2008-10-31)
The interaction of histone with nucleic acids was characterized by light-scattering measurement using a common spectrofluorometer. Thereby, a sensitive and convenient method for the determination of nucleic acids was established. At pH 4.5-6.5, the interaction of histone with nucleic acids
The EMBO journal, 38(21), e101365-e101365 (2019-08-31)
Inflammasomes are potent innate immune signalling complexes that couple cytokine release with pro-inflammatory cell death. However, pathogens have evolved strategies to evade this cell autonomous system. Here, we show how antibodies combine with innate sensors in primary human macrophages to
PLoS pathogens, 16(2), e1008151-e1008151 (2020-02-29)
HIV latency is the major barrier to a cure for people living with HIV (PLWH) on antiretroviral therapy (ART) because the virus persists in long-lived non-proliferating and proliferating latently infected CD4+ T cells. Latently infected CD4+ T cells do not
Cell reports, 26(9), 2377-2393 (2019-02-28)
Cytosolic DNA activates cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) synthase (cGAS), an innate immune sensor pivotal in anti-microbial defense, senescence, auto-immunity, and cancer. cGAS is considered to be a sequence-independent DNA sensor with limited access to nuclear DNA because of compartmentalization. However
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