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Merck
CN

D6783

Sigma-Aldrich

DL-二氢鞘氨醇

≥98%, synthetic

别名:

1,3-二羟基-2-氨基十八烷, DL-1,3-二羟基-2-氨基十八烷

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About This Item

经验公式(希尔记法):
C18H39NO2
CAS号:
分子量:
301.51
EC 号:
MDL编号:
UNSPSC代码:
12352211
PubChem化学物质编号:
NACRES:
NA.77

生物来源

synthetic

方案

≥98%

表单

solid

储存温度

−20°C

SMILES字符串

CCCCCCCCCCCCCCCC(O)C(N)CO

InChI

1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3

InChI key

OTKJDMGTUTTYMP-UHFFFAOYSA-N

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一般描述

二氢鞘氨醇是皮肤脂质屏障的重要组成部分,可保护人体免受过多的水分流失。

应用

DL-二氢鞘氨醇已用于引发酿酒酵母中的热应激信号。

生化/生理作用

鞘氨醇的生物合成前体。

其他说明

赤型和苏型异构体的混合物。标识在标签上的含量。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Phytosphingosine, sphingosine and dihydrosphingosine ceramides in model skin lipid membranes: permeability and biophysics
vSkolova B, et al.
Biochimica et Biophysica Acta - Biomembranes, 1859(5), 824-834 (2017)
A Kawamura et al.
Bioorganic & medicinal chemistry, 4(7), 1035-1043 (1996-07-01)
We have developed a simple picomole (low nanogram) scale HPLC scheme which can separate all eight isomers of sphingosine and dihydrosphingosine thus leading to the identification of their relative and absolute configurations. The amino group of the sample is derivatized
Sphingolipids Are Potential Heat Stress Signals inSaccharomyces
Dickson RC, et al.
The Journal of Biological Chemistry, 272(48), 30196-30200 (1997)
E M Raeder et al.
Blood, 93(2), 686-693 (1999-01-13)
In the present study, we investigated the mechanism by which sphingosine and its analogues, dihydrosphingosine and phytosphingosine, inhibit polymorphonuclear leukocyte (PMN) phagocytosis of IgG-opsonized erythrocytes (EIgG) and inhibit ERK1 and ERK2 phosphorylation. We used antibodies that recognized the phosphorylated forms
Lucila Gisele Pescio et al.
Journal of lipid research, 58(7), 1428-1438 (2017-05-19)
Ceramides (Cers) and complex sphingolipids with defined acyl chain lengths play important roles in numerous cell processes. Six Cer synthase (CerS) isoenzymes (CerS1-6) are the key enzymes responsible for the production of the diversity of molecular species. In this study

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