推荐产品
质量水平
方案
≥98% (HPLC)
表单
solid
颜色
yellow
溶解性
DMSO: ~28 mg/mL
H2O: insoluble
储存温度
2-8°C
SMILES字符串
COc1cccc(\C=N\N=C\c2cccc(OC)c2)c1
InChI
1S/C16H16N2O2/c1-19-15-7-3-5-13(9-15)11-17-18-12-14-6-4-8-16(10-14)20-2/h3-12H,1-2H3/b17-11+,18-12+
InChI key
FBNPHFBYHYNMHC-JYFOCSDGSA-N
生化/生理作用
Negative allosteric modulator at the metabotropic glutamate receptor mGluR5.
特点和优势
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
警示用语：
Danger
危险声明
危险分类
Aquatic Acute 1 - Eye Dam. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5.
Julie A O'Brien et al.
Molecular pharmacology, 64(3), 731-740 (2003-08-16)
We have identified a family of highly selective allosteric modulators of the group I metabotropic glutamate receptor subtype 5 (mGluR5). This family of closely related analogs exerts a spectrum of effects, ranging from positive to negative allosteric modulation, and includes
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