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Merck
CN

D5764

Sigma-Aldrich

2,3-二磷酸-D-甘油酸 五钠盐

glycolysis metabolite

别名:

2,3-DPG, D-甘油酸-2,3-二磷酸 钠盐

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About This Item

线性分子式:
C3H3O10P2Na5
分子量:
375.95
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25

生物来源

synthetic

质量水平

形式

powder

杂质

3-phosphoglyceric acid, essentially free

颜色

white to off-white

溶解性

water: 100 mg/mL, clear, colorless to faintly yellow

痕量阳离子

Na: 24.5-32.5% (anhydrous)

储存温度

−20°C

SMILES字符串

[Na].OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O

InChI

1S/C3H8O10P2.Na.H/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8;;/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11);;/t2-;;/m1../s1

InChI key

JJEMSNINYKJOBZ-YBBRRFGFSA-N

应用

D-甘油酸2,3-二磷酸酯是磷酸甘油酸变位酶和血红蛋白的辅因子,可用作分析血细胞(红细胞)糖酵解循环代谢物的参考化合物。

生化/生理作用

人体红细胞内的糖酵解代谢物由2,3-二磷酸甘油酸变位酶产生,代替糖酵解途径。与血红蛋白结合以减少氧合作用。

其他说明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Commercial blood bags are predominantly made of polyvinyl chloride (PVC) plasticized with di(2-ethylhexyl) phthalate (DEHP). DEHP is favourable for storage of red blood cells (RBC). Historically, removal of DEHP from blood bags has been linked to unacceptable haemolysis levels. Oncoming
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Transfusion, 57(8), 1905-1911 (2017-04-30)
No former studies have examined how blood donation influences physical performance in women, who due to menstruation may have a slower recovery of performance. Therefore, the aim of this study was to clarify how VO VO VO VO
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Science advances, 6(12), eaaw9679-eaaw9679 (2020-03-29)
Rhesus D (RhD) is one of the most important immunogenic antigens on red blood cells (RBCs). However, the supply of RhD-negative blood frequently faces critical shortages in clinical practice, and the positive-to-negative transition of the RhD antigen remains a great
Minke A E Rab et al.
American journal of hematology, 94(5), 575-584 (2019-02-21)
In sickle cell disease (SCD), sickle hemoglobin (HbS) polymerizes upon deoxygenation, resulting in sickling of red blood cells (RBCs). These sickled RBCs have strongly reduced deformability, leading to vaso-occlusive crises and chronic hemolytic anemia. To date, there are no reliable
Manon Bardyn et al.
Metabolites, 10(6) (2020-06-04)
After blood donation, the red blood cells (RBCs) for transfusion are generally isolated by centrifugation and then filtrated and supplemented with additive solution. The consecutive changes of the extracellular environment participate to the occurrence of storage lesions. In this study

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