所有图片(2)
About This Item
线性分子式:
C31H54N7O17P3S
CAS号:
分子量:
939.80
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
质量水平
检测方案
≥90%
形式
powder
储存温度
−20°C
SMILES字符串
O.CCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@H](O)C(C)(C)COP(O)(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1OP(O)(O)=O)n2cnc3c(N)ncnc23
InChI
1S/C31H54N7O17P3S.H2O/c1-4-5-6-7-8-9-10-11-22(40)59-15-14-33-21(39)12-13-34-29(43)26(42)31(2,3)17-52-58(49,50)55-57(47,48)51-16-20-25(54-56(44,45)46)24(41)30(53-20)38-19-37-23-27(32)35-18-36-28(23)38;/h18-20,24-26,30,41-42H,4-17H2,1-3H3,(H,33,39)(H,34,43)(H,47,48)(H,49,50)(H2,32,35,36)(H2,44,45,46);1H2/t20-,24-,25-,26+,30-;/m1./s1
InChI key
IRILGPHKFKSRQN-ASEPKIFHSA-N
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一般描述
癸酰辅酶A是酰基转移酶的底物。 它是人肝脏甘氨酸-N-酰基转移酶的底物。
应用
癸酰辅酶A一水合物已被用于磷脂酰肌醇-4,5-二磷酸盐的抑制研究（LC-CoA） 和人二酰基甘油酰基转移酶1和2测定中。
癸酰辅酶A（癸酰CoA）可通过霍乱弧菌CqsA酶与S-腺苷甲硫氨酸（SAM）偶联，产生有效的群体感应分子3-氨基三嗪-2-烯-4-酮（Ea-CAI-1。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA.
Kelly RC, Bolitho ME, Higgins DA, et al.
Nature Cell Biology, 5, 891-895 (2009)
J Mikkelsen et al.
The Biochemical journal, 227(3), 981-985 (1985-05-01)
Competitive binding experiments with malonyl-CoA and [1-14C]acetyl-CoA, [1-14C]butyryl-CoA or [1-14C]decanoyl-CoA indicate that all these substrates are transferred to lactating-goat mammary-gland fatty acid synthetase by the same transferase. Isolation and determination of the amino acid sequence of [1-14C]decanoyl-labelled CNBr-cleavage peptide from
N M Broadway et al.
The Biochemical journal, 322 ( Pt 2), 435-440 (1997-03-01)
We have investigated the extent to which membrane environment affects the catalytic properties of the malonyl-CoA-sensitive carnitine acyltransferase of liver microsomal membranes. Arrhenius-type plots of activity were linear in the absence and presence of malonyl-CoA (2.5 microM). Sensitivity to malonyl-CoA
J B McMillin et al.
Archives of biochemistry and biophysics, 312(2), 375-384 (1994-08-01)
An understanding of the mechanism of malonyl-CoA interaction with carnitine palmitoyltransferase (CPT-I) in isolated mitochondria is complicated by membrane fragmentation and CPT-II exposure. Using cultured neonatal rat cardiac myocytes, as in situ model was developed to measure CPT-I. In the
A Novel Acyl-CoA: Diacylglycerol Acyltransferase 1 (DGAT1) inhibitor, GSK2973980A, Inhibits Postprandial Triglycerides and Reduces Body Weight in a Rodent Diet-Induced Obesity Model
Kumar S, et al.
Journal of Pharmaceutical Research International, 18(1) (2017)
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