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Merck
CN

D5018

Sigma-Aldrich

3,4-Dehydro-L-proline methyl ester hydrochloride

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About This Item

经验公式(希尔记法):
C6H9NO2 · HCl
CAS号:
分子量:
163.60
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

表单

solid

储存温度

−20°C

SMILES字符串

Cl.COC(=O)C1NCC=C1

InChI

1S/C6H9NO2.ClH/c1-9-6(8)5-3-2-4-7-5;/h2-3,5,7H,4H2,1H3;1H

InChI key

LDWTUXKKNIHFQG-UHFFFAOYSA-N

生化/生理作用

3,4-Dehydro-L-proline methyl ester is C-terminal blocked 3,4-Dehydro-L-proline (3,4-DHP). 3,4-Dehydro-L-proline is used as a substrate and inhibitor of various enzymes. 3,4-Dehydro-L-proline may be used to inhibit extensin biosynthesis. 3,4-Dehydro-L-proline is a alternate substrate of the amino acid oxidase, NikD. 3,4-Dehydro-L-proline inhibits collagen secretion by chondorcytes.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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Developmental localization and the role of hydroxyproline rich glycoproteins during somatic embryogenesis of banana (Musa spp. AAA).
Xu C, Takac T, Burbach C, et al.
BMC plant biology, 24, 38-38 (2011)
Phaneeswara-Rao Kommoju et al.
Biochemistry, 48(40), 9542-9555 (2009-08-26)
NikD is a flavoprotein oxidase that catalyzes the oxidation of piperideine-2-carboxylate (P2C) to picolinate in a remarkable aromatization reaction comprising two redox cycles and at least one isomerization step. Tyr258 forms part of an "aromatic cage" that surrounds the ring
Annick Méjean et al.
Biochemistry, 49(1), 103-113 (2009-12-04)
Anatoxin-a and homoanatoxin-a are two potent cyanobacterial neurotoxins. We recently reported the identification of the gene cluster responsible for the biosynthesis of these toxins in cyanobacteria and proposed a biosynthetic scheme starting from L-proline and involving three polyketide synthases for
Hyon Jong Kim et al.
The Journal of biological chemistry, 283(16), 10310-10317 (2008-02-19)
Physiological mineralization in growth plate cartilage is highly regulated and restricted to terminally differentiated chondrocytes. Because mineralization occurs in the extracellular matrix, we asked whether major extracellular matrix components (collagens) of growth plate cartilage are directly involved in regulating the

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