所有图片(1)
别名:
DSIP, Emideltide, Sleep inducing peptide, Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
经验公式（希尔记法）:
C35H48N10O15
推荐产品
形式
powder
质量水平
储存温度
−20°C
SMILES字符串
C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(O)=O
InChI
1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)/t16-,17-,20-,22-,23-,24-/m0/s1
InChI key
ZRZROXNBKJAOKB-GFVHOAGBSA-N
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Amino Acid Sequence
Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH
一般描述
Delta sleep inducing peptide (DSIP) is a nonapeptide which was isolated from the rabbit brain. It is synthesized in the hypothalamus and is present in small amounts in the blood.
生化/生理作用
DSIP promotes sleep by targeting various areas of the brain. The peptide is easily absorbed from the gut and is not denatured by enzymes. It crosses the blood-brain barrier easily. DSIP influences the circadian rhythm in humans. Low concentrations of the peptide are observed in patients with schizophrenia and depression.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
监管及禁止进口产品
Joo Sung Kim et al.
Macromolecular bioscience, 20(11), e2000147-e2000147 (2020-07-15)
Mechanoreceptors in human skin possess high sensitivity, wide sensing range, and high sensing resolution for external stimuli. Several attempts have been made to implement electronic skin (e-skin) that can mimic human skin. However, previous attempts are limited by the fundamental
Delta sleep-inducing peptide
Pollard BJ and Pomfrett CJD
European Journal of Anaesthesiology, 18(7), 419-422 (2001)
Piia Liigand et al.
Journal of mass spectrometry : JMS, 54(6), 481-487 (2019-03-09)
Electrospray ionization is widely used to generate gas phase ions from a variety of molecules ranging from small ions to large proteins, while the ionization mechanism is claimed to depend on the size of the molecule. For small molecules, the
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