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Merck
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文件

安全信息

D3676

Sigma-Aldrich

10-脱乙酰基巴卡汀III 来源于浆果紫杉

≥95% (HPLC)

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经验公式（希尔记法）:
C29H36O10
CAS号:
32981-86-5
分子量:
544.59
MDL编号:
MFCD00132913
UNSPSC代码:
51101500
PubChem化学物质编号:
24893778
NACRES:
NA.85

生物来源

Taxus baccata

质量水平

200

检测方案

≥95% (HPLC)

形式

solid

分子量

544.59 g/mol

颜色

white

溶解性

methanol: soluble, clear, colorless (5 mg + 0.1 mL MeOH)

抗生素抗菌谱

neoplastics

作用机制

DNA synthesis | interferes

储存温度

2-8°C

SMILES字符串

[H][C@@]12C[C@H](O)[C@@]3(C)C(=O)[C@H](O)C4=C(C)[C@@H](O)C[C@@](O)([C@@H](OC(=O)c5ccccc5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C

InChI

1S/C29H36O10/c1-14-17(31)12-29(36)24(38-25(35)16-9-7-6-8-10-16)22-27(5,23(34)21(33)20(14)26(29,3)4)18(32)11-19-28(22,13-37-19)39-15(2)30/h6-10,17-19,21-22,24,31-33,36H,11-13H2,1-5H3/t17-,18-,19+,21+,22-,24-,27+,28-,29+/m0/s1

InChI key

YWLXLRUDGLRYDR-ZHPRIASZSA-N

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相关类别

应用

10-脱乙酰基浆果赤霉素III被用作制备抗癌药物紫杉醇（紫杉醇）的一种化学中间体。它被用于研究紫杉醇生物合成途径。

生化/生理作用

10-脱乙酰基浆果赤霉素III是紫杉醇生物合成的第五中间体。该生物合成通路由大约20个尚未被完全阐明的酶促步骤组成。

象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Danger

危险分类

Carc. 1B - Eye Irrit. 2 - Muta. 1B - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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